4377-63-3 Usage
General Description
6-Chlorochroman-2-one, also known as 5,6-dihydro-6-chloro-4H-chromen-2-one, is a synthetic chemical compound with the molecular formula C9H7ClO2. It belongs to the class of chromanone compounds and is a derivative of chromone. It is commonly used as a building block in the synthesis of various pharmaceuticals and agrochemicals due to its ability to modulate biological processes. Its structure consists of a chloro-substituted chromanone ring, which makes it a valuable intermediate in the production of diverse functionalized molecules. The compound has potential applications in the development of drugs for various therapeutic areas, including anticancer, anti-inflammatory, and antiviral agents. Additionally, it is used as a research tool in chemical and biological studies.
Check Digit Verification of cas no
The CAS Registry Mumber 4377-63-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,3,7 and 7 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 4377-63:
(6*4)+(5*3)+(4*7)+(3*7)+(2*6)+(1*3)=103
103 % 10 = 3
So 4377-63-3 is a valid CAS Registry Number.
4377-63-3Relevant articles and documents
Effet de groupe partant dans l'hydrolyse d'orthoesters cycliques: changement de conformere reactif dans l'hydrolyse des diethoxy-2,2 tetrahydropyrannes
Lamaty, Gerard,Lorente, Philippe,Moreau, Claude
, p. 2651 - 2656 (2007/10/02)
The rates of hydrolysis of 6-substituted 2,2-diethoxy-3,4-dihydrobenzo-1-pyrans (X=MeO, Me, H, Cl) were determined at two temperatures in water/dioxan 2:1 by volume.The observed change of sign of the Hammett ρ constants (ρH3O+=-0.8; ρAH=0.7) is characteristic of a phenolate leaving group, i.e. of the rate-determining cleavage of the endocyclic C-O bond in the systems here studied; these results cleary indicate a change in the nature of the reactive conformer in hydrolysis of 2,2-diethoxy tetrahydropyrans.
