437701-80-9

Basic information

• Product Name: 1H-Pyrazole-4-carboxamide
• Synonyms: 1H-Pyrazole-4-carboxamide;4-PyrazolecarboxaMide
• CAS NO: 437701-80-9
• Molecular Formula: C₄H₅N₃O
• Molecular Weight: 111.102
• Mol File: 437701-80-9.mol
• Article Data: 5

Chemical Properties

• Melting Point: 225-227 °C(Solv: ethanol (64-17-5))
• Boiling Point: 469.6±18.0 °C(Predicted)
• Appearance: /
• Density: 1.394±0.06 g/cm3(Predicted)
• PKA: 11.98±0.50(Predicted)
• CAS DataBase Reference: 1H-Pyrazole-4-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrazole-4-carboxamide(437701-80-9)
• EPA Substance Registry System: 1H-Pyrazole-4-carboxamide(437701-80-9)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 437701-80-9(Hazardous Substances Data)

Usage

General Description

1H-Pyrazole-4-carboxamide, also known as 4-Pyrazolamide, is a chemical compound with the molecular formula C4H5N3O. It is a white to off-white solid and is commonly used in the synthesis of various pharmaceuticals. 1H-Pyrazole-4-carboxamide has been researched for its potential applications in the treatment of tuberculosis, as well as other medical conditions. It has also been studied for its potential antifungal and antibacterial properties. 1H-Pyrazole-4-carboxamide is considered to be a versatile building block in organic synthesis, making it a valuable compound in the field of medicinal and pharmaceutical chemistry.

Upstream product

• 37718-11-9 1H-pyrazole-4-carboxylic acid 
• 37622-90-5 4-ethoxycarbonylpyrazole 
• 1234737-38-2 N-(hydrazonomethyl)-1H-pyrazole-4-carboxamide 

Downstream Products

• 1234737-53-1 4-aminocarbonyl-N-[4-chloro-3-(trifluoromethyl)phenyl]-1H-pyrazole-1-acetamide 
• 1234737-55-3 4-aminocarbonyl-N-(2,4-dichlorophenyl)-1H-pyrazole-1-acetamide 
• 1234737-54-2 4-aminocarbonyl-N-(4-methylphenyl)-1H-pyrazole-1-acetamide 
• 1234737-56-4 4-aminocarbonyl-N-(4-chlorophenyl)-1H-pyrazole-1-acetamide 

Relevant articles and documents

OXAZOLE DERIVATIVES USEFUL AS INHIBITORS OF FAAH

The present invention is directed to certain oxazole derivatives which are useful as inhibitors of Fatty Acid Amide Hydrolase (FAAH). The invention is also concerned with pharmaceutical formulations comprising these compounds as active ingredients and the use of the compounds and their formulations in the treatment of certain disorders, including osteoarthritis, rheumatoid arthritis, diabetic neuropathy, postherpetic neuralgia, skeletomuscular pain, and fibromyalgia, as well as acute pain, migraine, sleep disorder, Alzheimer Disease, and Parkinson's Disease.

OXAZOLE DERIVATIVES USEFUL AS INHIBITORS OF FAAH

The present invention is directed to certain oxazole derivatives which are useful as inhibitors of Fatty Acid Amide Hydrolase (FAAH). The invention is also concerned with pharmaceutical formulations comprising these compounds as active ingredients and the use of the compounds and their formulations in the treatment of certain disorders, including osteoarthritis, rheumatoid arthritis, diabetic neuropathy, postherpetic neuralgia, skeletomuscular pain, and fibromyalgia, as well as acute pain, migraine, sleep disorder, Alzeimer Disease, and Parkinson's Disease.

DERIVATIVES OF IMIDAZO (1,2-A) PYRIDINE USEFUL AS MEDICAMENTS FOR TREATING GASTROINTESTINAL DISEASES

This invention relates to newly identified imidazopyridine compounds of formula (I), to the use of such compounds in therapy and to their production.