438554-29-1

Basic information

• Product Name: N-(3-ethylamino-pyridin-4-yl)-2-(2-thiazol-2-yl-imidazol-1-yl)-acetamide
• CAS NO: 438554-29-1
• Molecular Weight: 328.398
• Mol File: 438554-29-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-(3-ethylamino-pyridin-4-yl)-2-(2-thiazol-2-yl-imidazol-1-yl)-acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(3-ethylamino-pyridin-4-yl)-2-(2-thiazol-2-yl-imidazol-1-yl)-acetamide(438554-29-1)
• EPA Substance Registry System: N-(3-ethylamino-pyridin-4-yl)-2-(2-thiazol-2-yl-imidazol-1-yl)-acetamide(438554-29-1)

Safety Data

• Hazardous Substances Data: 438554-29-1(Hazardous Substances Data)

Upstream product

• 438564-56-8 (2-thiazol-2-yl-imidazol-1-yl)-acetic acid methyl ester 
• 61719-62-8 N-3-ethyl-pyridine-3,4-diamine 
• 14043-25-5 3-ethylamino-4-nitropyridine N-oxide 

Relevant articles and documents

Benzimidazole and pyridylimidazole derivatives

This invention relates to benzimidazoles, pyridylimidazoles and related bicyclic heteroaryl compounds, all of which may be described by of Formula I The invention is particularly related to such compounds that bind with high selectivity and high affinity to the benzodiazepine site of GABAA receptors. This invention also relates to pharmaceutical compositions comprising such compounds and to the use of such compounds in treatment of certain central nervous system (CNS) diseases. Novel processes for preparing compounds of Formula I are disclosed. This invention also relates to the use of benzimidazoles, pyridylimidazoles and related bicyclic heteroaryl compounds of Formula I in combination with one or more other CNS agents to potentiate the effects of the other CNS agents. Additionally this invention relates to the use such compounds as probes for the localization of GABAA receptors in tissue sections.