439242-00-9Relevant articles and documents
First total synthesis of natural aplyolides B and D, ichthyotoxic macrolides isolated from the skin of the marine mollusk Aplysia depilans
Spinella, Aldo,Caruso, Tonino,Coluccini, Carmine
, p. 1681 - 1683 (2002)
A convergent pathway is described for the synthesis of the marine macrolides aplyolides B (2) and D (3). Stereoselective preparation of a key fragment was achieved by Sharpless asymmetric dihydroxylation of eneyne 10.