439692-55-4

Basic information

• Product Name: 6-TERT-BUTYL-4-CHLOROTHIENO[2,3-D]PYRIMIDINE
• Synonyms: 6-TERT-BUTYL-4-CHLOROTHIENO[2,3-D]PYRIMIDINE;4-Chloro-6-(1,1-dimethylethyl)-thieno[2,3-d]pyrimidine
• CAS NO: 439692-55-4
• Molecular Formula: C10H11ClN2S
• Molecular Weight: 226.73
• Mol File: 439692-55-4.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 321.7±37.0 °C(Predicted)
• Appearance: /
• Density: 1.272
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 0.62±0.40(Predicted)
• CAS DataBase Reference: 6-TERT-BUTYL-4-CHLOROTHIENO[2,3-D]PYRIMIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 6-TERT-BUTYL-4-CHLOROTHIENO[2,3-D]PYRIMIDINE(439692-55-4)
• EPA Substance Registry System: 6-TERT-BUTYL-4-CHLOROTHIENO[2,3-D]PYRIMIDINE(439692-55-4)

Safety Data

• Hazardous Substances Data: 439692-55-4(Hazardous Substances Data)

Usage

General Description

The chemical 6-Tert-Butyl-4-Chlorothieno[2,3-D]Pyrimidine is a heterocyclic compound with a thieno-pyrimidinone structure that consists of a thiophene ring fused to a pyrimidine ring, substituted with a tert-butyl group at the 6-position and a chlorine atom at the 4-position. 6-TERT-BUTYL-4-CHLOROTHIENO[2,3-D]PYRIMIDINE is used in the pharmaceutical industry as a building block for the synthesis of various pharmaceutical compounds. It is also used as a ligand in metal-catalyzed reactions and as a research tool in chemical biology. The chemical properties and reactivity of 6-Tert-Butyl-4-Chlorothieno[2,3-D]Pyrimidine make it a valuable component for the development of novel drug candidates and organic synthesis.

Upstream product

• 439692-54-3 6-tert-butyl-4-oxothieno[2,3-d]pyrimidine 
• 175137-03-8 methyl 3-amino-5-tert-butylthiophene-2-carboxylate 
• 216574-71-9 2-amino-5-tert-butylthiophene-3-carboxylic acid methyl ester 

Relevant articles and documents

Thiophene [2, 3 - d] pyrimidine derivatives, their preparation and use thereof

The invention provides a thiophene [2, 3-d] pyrimidine derivative containing isoxazole heterocycle shown by formula (I) or a pharmaceutically accepted salt thereof, wherein R1 and R2 are respectively selected from hydrogen, C1-6 alkyl, C1-6 alkoxy, haloge

Discovery of novel thieno[2,3-d]pyrimidin-4-yl hydrazone-based inhibitors of Cyclin D1-CDK4: Synthesis, biological evaluation and structure-activity relationships. Part 2

The design, synthesis and evaluation of novel thieno[2,3-d]pyrimidin-4-yl hydrazone analogues as cyclin-dependent kinase 4 (CDK4) inhibitor are described. Focusing on the optimization of the heteroaryl moiety at the hydrazone with substituted phenyl group