439697-24-2Relevant articles and documents
Synthesis of aminoglycoside-DNA conjugates
Charles,Xue, Liang,Arya, Dev P.
, p. 1259 - 1262 (2002)
Development of aminoglycoside-nucleic acid conjugates is presented. Synthesis of a DNA dimer covalently linked to kanamycin and neomycin isothiocyanates has been carried out. The development of such conjugates will help couple the sequence specificity of nucleic acids to the electrostatic/shape complementarity of aminoglycoside antibiotics in binding nucleic acid targets.