439940-48-4Relevant articles and documents
Incremental conversion of outer-membrane permeabilizers into potent antibiotics for gram-negative bacteria
Li, Chunhong,Budge, Loren P.,Driscoll, Collin D.,Willardson, Barry M.,Allman, Glenn W.,Savage, Paul B.
, p. 931 - 940 (1999)
Cholic acid derivatives appended with amine groups have been prepared for use as permeabilizers of the outer membranes of Gram-negative bacteria. These compounds interact synergistically with antibiotics such as erythromycin and novobiocin to inhibit grow
Cationic Steroid Antimicrobial Compositions and Methods of Use
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Page/Page column 20; 39, (2010/11/28)
The invention provides methods for decreasing or inhibiting human immunodeficiency virus (HIV) infection or pathogenesis (e.g., illness) of a cell in vitro, ex vivo or in vivo, a symptom or pathology associated with human immunodeficiency virus (HIV) infection or pathogenesis (e.g., illness) in vitro, ex vivo or in vivo, or an adverse side effect of human immunodeficiency virus (HIV) infection or pathogenesis (e.g., illness) in vitro, ex vivo or in vivo. In one embodiment, a method of the invention includes treating a subject with an invention compound (e.g., cationic steroid antimicrobial or CSA).
Cationic Steroid Microbial Compositions and Methods of Use
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Page/Page column 19; 38, (2010/11/28)
The invention relates to methods for decreasing or inhibiting influenza virus infection or pathogenesis of a cell in vitro, ex vivo or in vivo, a symptom or pathology associated with influenza infection or pathogenesis in vitro, ex vivo or in vivo, or an adverse side effect of influenza infection or pathogenesis in vitro, ex vivo or in vivo. In one embodiment, a method of the invention includes treating a subject with an invention compound (e.g., cationic steroid antimicrobial or CSA).