4400-05-9 Usage
Physical appearance
White to off-white crystalline powder.
Odor
Mild characteristic odor.
Usage
Antifungal and antimicrobial agent in personal care products (e.g. soaps, shampoos, and skin care products).
Industrial applications
Preservative in paints, adhesives, and coatings.
Mechanism of action
Disrupts the cell membranes of microorganisms, preventing their growth and reproduction.
Potential health risks
Skin and eye irritation.
Environmental impact
Regulated in various countries due to its potential negative effects.
Regulatory status
Use of bromophen in consumer products is regulated in different countries.
Check Digit Verification of cas no
The CAS Registry Mumber 4400-05-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,4,0 and 0 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 4400-05:
(6*4)+(5*4)+(4*0)+(3*0)+(2*0)+(1*5)=49
49 % 10 = 9
So 4400-05-9 is a valid CAS Registry Number.
InChI:InChI=1/C12H8Br2O/c13-10-6-9(7-11(14)12(10)15)8-4-2-1-3-5-8/h1-7,15H
4400-05-9Relevant articles and documents
Selective and efficient generation of ortho-brominated para-substituted phenols in ACS-grade methanol
Georgiev, David,Saes, Bartholomews W.H.,Johnston, Heather J.,Boys, Sarah K.,Healy, Alan,Hulme, Alison N.
, (2016/02/05)
The mono ortho-bromination of phenolic building blocks by NBS has been achieved in short reaction times (15-20 min) using ACS-grade methanol as a solvent. The reactions can be conducted on phenol, naphthol and biphenol substrates, giving yields of >86% on gram scale. Excellent selectivity for the desired mono ortho-brominated products is achieved in the presence of 10 mol % para-TsOH, and the reaction is shown to be tolerant of a range of substituents, including CH3/ F,and NHBoc.
