440104-25-6Relevant articles and documents
Total Synthesis of Ionomycin Using Ring-Opening Strategies
Lautens, Mark,Colucci, John T.,Hiebert, Sheldon,Smith, Nicholas D.,Bouchain, Giliane
, p. 1879 - 1882 (2007/10/03)
(Matrix Presented) The total synthesis of the polyether antibiotic ionomycin, a calcium ionophore, is described. The synthesis demonstrates the utility of ring-opening methodologies as applied to the synthesis of polypropionate and deoxypolypropionate subunits, which are found in two of the four fragments in the synthesis.