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4405-08-7

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4405-08-7 Usage

Description

(4,6-DIAMINO-1,3,5-TRIAZINE-2-YL)GUANIDINE, also known as Guanylmelamine, is a guanidino compound derived from the triazine class of organic compounds. It possesses significant antitumor activity and is recognized as a neoplasm inhibitor. Its chemical structure allows it to interact with various biological targets, making it a promising candidate for pharmaceutical applications.

Uses

Used in Anticancer Applications:
(4,6-DIAMINO-1,3,5-TRIAZINE-2-YL)GUANIDINE is used as an anticancer agent for its potent antitumor activity. It is particularly effective against various types of cancer, including solid malignancies. (4,6-DIAMINO-1,3,5-TRIAZINE-2-YL)GUANIDINE works by inhibiting the growth and progression of tumor cells, making it a valuable addition to the arsenal of cancer-fighting drugs.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, (4,6-DIAMINO-1,3,5-TRIAZINE-2-YL)GUANIDINE is used as a neoplasm inhibitor. Its ability to target and inhibit the development of tumors makes it a crucial component in the development of new cancer treatments. (4,6-DIAMINO-1,3,5-TRIAZINE-2-YL)GUANIDINE's unique properties also make it a subject of interest for further research and potential drug development.
Used in Drug Delivery Systems:
Similar to gallotannin, (4,6-DIAMINO-1,3,5-TRIAZINE-2-YL)GUANIDINE can also be incorporated into drug delivery systems to enhance its efficacy and bioavailability. By employing various organic and metallic nanoparticles as carriers, the compound's delivery to target cancer cells can be improved, leading to better therapeutic outcomes and potentially reducing side effects.

Check Digit Verification of cas no

The CAS Registry Mumber 4405-08-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,4,0 and 5 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 4405-08:
(6*4)+(5*4)+(4*0)+(3*5)+(2*0)+(1*8)=67
67 % 10 = 7
So 4405-08-7 is a valid CAS Registry Number.

4405-08-7Synthetic route

N-Cyanoguanidine
127099-85-8, 780722-26-1

N-Cyanoguanidine

A

2,4-diamino-6-guanidino-1,3,5-triazine
4405-08-7

2,4-diamino-6-guanidino-1,3,5-triazine

B

carbamimidoylurea
141-83-3

carbamimidoylurea

C

2,4,6-triguanidino-1,3,5-triazine
32151-75-0

2,4,6-triguanidino-1,3,5-triazine

D

guanidine nitrate
113-00-8

guanidine nitrate

Conditions
ConditionsYield
With hydrogenchloride In N,N-dimethyl-formamide at 80℃; for 0.5h;A 8%
B n/a
C 42%
D n/a
With hydrogenchloride In N,N-dimethyl-formamide at 80℃; for 1.83333h; Yield given;A 8%
B n/a
C 42%
D n/a
2-Chloro-4,6-diamino-1,3,5-triazine
3397-62-4

2-Chloro-4,6-diamino-1,3,5-triazine

diguanidine carbonate
593-85-1

diguanidine carbonate

2,4-diamino-6-guanidino-1,3,5-triazine
4405-08-7

2,4-diamino-6-guanidino-1,3,5-triazine

cyanomelamine
3496-98-8

cyanomelamine

ammonium acetate
631-61-8

ammonium acetate

2,4-diamino-6-guanidino-1,3,5-triazine
4405-08-7

2,4-diamino-6-guanidino-1,3,5-triazine

Conditions
ConditionsYield
With ethylene glycol
N-Cyanoguanidine
127099-85-8, 780722-26-1

N-Cyanoguanidine

A

2,4-diamino-6-guanidino-1,3,5-triazine
4405-08-7

2,4-diamino-6-guanidino-1,3,5-triazine

B

4,6-diguanidino-<1,3,5>triazin-2-ylamine, triguanidino-<1,3,5>triazine

4,6-diguanidino-<1,3,5>triazin-2-ylamine, triguanidino-<1,3,5>triazine

Conditions
ConditionsYield
With hydrogenchloride; phenol
With hydrogen fluoride; phenol
hydrogenchloride
7647-01-0

hydrogenchloride

N-Cyanoguanidine
127099-85-8, 780722-26-1

N-Cyanoguanidine

phenol
108-95-2

phenol

A

2,4-diamino-6-guanidino-1,3,5-triazine
4405-08-7

2,4-diamino-6-guanidino-1,3,5-triazine

B

N,N'''-(6-amino-[1,3,5]triazine-2,4-diyl)-bis-guanidine
26690-75-5

N,N'''-(6-amino-[1,3,5]triazine-2,4-diyl)-bis-guanidine

C

2,4,6-triguanidino-1,3,5-triazine
32151-75-0

2,4,6-triguanidino-1,3,5-triazine

Conditions
ConditionsYield
at 120℃;

4405-08-7Downstream Products

4405-08-7Relevant articles and documents

Synthesis of Guanidino-1,3,5-triazines Using DMF

Iio, Kokoro,Ichikawa, Eiichi

, p. 2735 - 2736 (2007/10/02)

2,4,6-Triguanidino-1,3,5-triazine and 2,4,6-tris(3-methylguanidino)-1,3,5-triazine were synthesized in 42 and 52percent yields, respectively, by the cyclotrimerization of cyanoguanidine and 1-methyl-3-cyanoguanidine using DMF as a solvent in the presence of hydrogen chloride. 1-Phenyl-3-cyanoguanidine, 1,2-dimethyl-3-cyanoguanidine, and 2-imidazolidinylidenecyanamide, however, were cyclodimerized to the corresponding guanidino-1,3,5-triazines in a similar manner.

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