440678-63-7

Basic information

• Product Name: 1,2-Pyrrolidinedicarboxylic acid, 4-hydroxy-, 1-(1,1-dimethylethyl) 2-ethyl ester, (2S,4S)-
• CAS NO: 440678-63-7
• Molecular Formula: C12H21NO5
• Molecular Weight: 259.302
• Mol File: 440678-63-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1,2-Pyrrolidinedicarboxylic acid, 4-hydroxy-, 1-(1,1-dimethylethyl) 2-ethyl ester, (2S,4S)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-Pyrrolidinedicarboxylic acid, 4-hydroxy-, 1-(1,1-dimethylethyl) 2-ethyl ester, (2S,4S)-(440678-63-7)
• EPA Substance Registry System: 1,2-Pyrrolidinedicarboxylic acid, 4-hydroxy-, 1-(1,1-dimethylethyl) 2-ethyl ester, (2S,4S)-(440678-63-7)

Safety Data

• Hazardous Substances Data: 440678-63-7(Hazardous Substances Data)

Usage

Explanation

This is the full IUPAC name of the compound, which describes its structure and stereochemistry.

Explanation

The molecular formula represents the number of atoms of each element present in the compound.

Explanation

These are the functional groups present in the compound, which contribute to its chemical properties and reactivity.

Explanation

The stereochemistry of the compound is indicated by the (2S,4S)notation, which describes the spatial arrangement of the atoms in the molecule.

Explanation

The compound is used in the pharmaceutical industry as a chiral building block, which is a key component in the synthesis of various pharmaceutical drugs.

Explanation

The compound is synthesized by attaching a hydroxy and ethyl group to the 4th and 2nd positions of 1,2-pyrrolidinedicarboxylic acid, respectively.

Explanation

The compound has potential therapeutic applications in the medical field due to its pharmacological properties, which may include its ability to interact with biological targets and produce desired effects.

Explanation

The chirality of the compound, as indicated by the (2S,4S)notation, is important for its biological activity, as different stereoisomers may have different effects on biological systems.

Explanation

The compound is likely to be soluble in organic solvents, such as ethanol or methanol, due to its ester and hydroxy functional groups.

Explanation

The compound is expected to be stable under normal conditions, such as room temperature and pressure, as it does not contain any highly reactive functional groups.

Functional Groups

Ester, Hydroxy, Carboxylic Acid

Stereochemistry

(2S,4S)-

Pharmaceutical Industry

Used as a chiral building block

Synthesis

Ester derivative of 1,2-pyrrolidinedicarboxylic acid

Therapeutic Applications

Potential due to pharmacological properties

Chirality

Important for biological activity

Solubility

Soluble in organic solvents

Stability

Stable under normal conditions

Upstream product

• 74-96-4 ethyl bromide 
• 87691-27-8 N-tert-butoxycarbonyl-L-cis-4-hydroxyproline 

Downstream Products

• 1252636-70-6 (2S,4S)-4-(3-Nitro-benzenesulfonyloxy)-pyrrolidine-1,2-dicarboxylic Acid 1-tert-butyl Ester 2-ethyl Ester 
• 404346-77-6 (1S,2S,6S,7aS)-1,2,6-trihydroxyhexahydro-1H-pyrrolizin-3-one 
• 147710-89-2 1-tert-butyl 2-ethyl-(2S,4S)-4-(((4-methylphenyl)sulfonyl)oxy)pyrrolidine-1,2-dicarboxylate 
• 618-27-9 hydroxy L-proline 
• 1023754-67-7 4-(3-benzoyl-5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-2-[(tert-butoxycarbonylmethyl-methyl-amino)-methyl]-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 887923-75-3 2-[(tert-butoxycarbonylmethyl-methyl-amino)-methyl]-4-(tert-butyl-diphenyl-silanyloxy)-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 887923-73-1 (2S,4S)-tert-butyl 4-(tert-butyldiphenylsilyloxy)-2-(hydroxymethyl)pyrrolidine-1-carboxylate 
• 887923-74-2 2-bromomethyl-4-(tert-butyl-diphenyl-silanyloxy)-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 87691-27-8 N-tert-butoxycarbonyl-L-cis-4-hydroxyproline 

Relevant articles and documents

NOVEL PROLINE DERIVATIVES

The invention relates to a compound of formula (I) wherein A, R1-R6 are as defined in the description and in the claims. The compound of formula (I) can be used as a medicament.