441771-60-4

Basic information

• Product Name: 3,6,9,12,15,18-Hexaoxanonadecane-1-thiol
• Synonyms: 3,6,9,12,15,18-Hexaoxanonadecane-1-thiol;2,5,8,11,14,17-Hexaoxanonadecane-19-thiol;MPEG6-SH;m-PEG6-thiol;2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethanethiol
• CAS NO: 441771-60-4
• Molecular Formula: C13H28O6S
• Molecular Weight: 312.42
• Mol File: 441771-60-4.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 383.7±42.0 °C(Predicted)
• Appearance: /
• Density: 1.057
• Storage Temp.: -20°C
• PKA: 9?+-.0.10(Predicted)
• CAS DataBase Reference: 3,6,9,12,15,18-Hexaoxanonadecane-1-thiol(CAS DataBase Reference)
• NIST Chemistry Reference: 3,6,9,12,15,18-Hexaoxanonadecane-1-thiol(441771-60-4)
• EPA Substance Registry System: 3,6,9,12,15,18-Hexaoxanonadecane-1-thiol(441771-60-4)

Safety Data

• Hazardous Substances Data: 441771-60-4(Hazardous Substances Data)

Usage

Description

3,6,9,12,15,18-Hexaoxanonadecane-1-thiol is a compound characterized by its unique structure, featuring a 19-carbon chain with six oxygen atoms interspersed throughout, and a thiol (-SH) group at the first carbon position. This structure endows it with specific chemical properties and reactivity, making it a versatile molecule for various applications.

Uses

Used in Bioconjugation:
3,6,9,12,15,18-Hexaoxanonadecane-1-thiol is used as a bioconjugation agent for the formation of stable and covalent bonds with other biomolecules, such as proteins, peptides, and nucleic acids. The thiol group in the molecule reacts with maleimide, OPSS, vinylsulfone, and transition metal surfaces, including gold and silver, allowing for the attachment of various functional groups and enhancing the biocompatibility and stability of the resulting conjugates.
Used in Drug Delivery:
3,6,9,12,15,18-Hexaoxanonadecane-1-thiol is employed as a component in drug delivery systems, where it serves as a crosslinker or a stabilizing agent. The hydrophilic PEG spacer in the molecule increases solubility in aqueous media, which is crucial for the development of drug delivery systems that can effectively encapsulate and release therapeutic agents.
Used in PEG Hydrogel:
3,6,9,12,15,18-Hexaoxanonadecane-1-thiol is used as a crosslinker in the formation of PEG hydrogels, which are versatile materials with applications in tissue engineering, drug delivery, and wound healing. The thiol group in the molecule can react with other thiol-containing molecules or with maleimide-functionalized PEG chains, creating a stable and biocompatible hydrogel network.
Used in Surface Functionalization:
3,6,9,12,15,18-Hexaoxanonadecane-1-thiol is utilized for surface functionalization of various materials, such as nanoparticles, microparticles, and planar surfaces. The thiol group in the molecule can bind to transition metal surfaces, allowing for the attachment of functional groups, biomolecules, or drugs to the surface, which can enhance the performance and biocompatibility of the material in various applications.