442156-86-7

Basic information

• Product Name: 3-(tert-butyl-diphenyl-silanyloxy)-2-[2-hydroxy-3-(6-oxo-6H-pyrimidin-1-yl)-propyl]-piperidine-1-carboxylic acid tert-butyl ester
• Synonyms: 3-(tert-butyl-diphenyl-silanyloxy)-2-[2-hydroxy-3-(6-oxo-6H-pyrimidin-1-yl)-propyl]-piperidine-1-carboxylic acid tert-butyl ester
• CAS NO: 442156-86-7
• Molecular Weight: 591.823
• Mol File: 442156-86-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-(tert-butyl-diphenyl-silanyloxy)-2-[2-hydroxy-3-(6-oxo-6H-pyrimidin-1-yl)-propyl]-piperidine-1-carboxylic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(tert-butyl-diphenyl-silanyloxy)-2-[2-hydroxy-3-(6-oxo-6H-pyrimidin-1-yl)-propyl]-piperidine-1-carboxylic acid tert-butyl ester(442156-86-7)
• EPA Substance Registry System: 3-(tert-butyl-diphenyl-silanyloxy)-2-[2-hydroxy-3-(6-oxo-6H-pyrimidin-1-yl)-propyl]-piperidine-1-carboxylic acid tert-butyl ester(442156-86-7)

Safety Data

• Hazardous Substances Data: 442156-86-7(Hazardous Substances Data)

Upstream product

• 442156-82-3 N-(tert-butoxycarbonyl)-3-(tert-butyldiphenylsilyl)oxy-2-(2,3-dihydroxypropyl)piperidine 
• 442156-77-6 4-(tert-butyldiphenylsilanyloxy)-1-(4-methoxybenzyloxy)-5-hexene 
• 442157-05-3 3-[3-(tert-butyl-diphenyl-silanyloxy)-piperidin-2-yl]-propane-1,2-diol 
• 442156-79-8 4-(tert-butyldiphenylsilyl)oxy-5-hexenyl methanesulfonate 
• 442156-81-2 methanesulfonic acid 4-(tert-butyl-diphenyl-silanyloxy)-5-oxo-pentyl ester 
• 154476-70-7 6-(4-methoxybenzyloxy)hex-1-en-3-ol 
• 113423-54-4 4-(tert-butyldiphenylsilyloxy)-5-hexen-1-ol 
• 51953-18-5 pyrimidine-4(3H)-one 
• 442156-84-5 N-(tert-butoxycarbonyl)-3-(tert-butyldiphenylsilyl)oxy-2-[(oxiranyl)methyl]piperidine 

Downstream Products

• 442156-88-9 3-(tert-butyl-diphenyl-silanyloxy)-2-[2-oxo-3-(6-oxo-6H-pyrimidin-1-yl)-propyl]-piperidine-1-carboxylic acid tert-butyl ester 

Relevant articles and documents

Potent antimalarial febrifugine analogues against the Plasmodium malaria parasite

Although febrifugine (1) and isofebrifugine (2), alkaloids isolated from roots of the Dichroa febrifuga plant, show powerful antimalarial activity against Plasmodium falciparum, strong side effects such as the emetic effect have precluded their clinical u