442562-83-6

Basic information

• Product Name: 4-(2,3-difluoro-phenyl)-1H-indole
• Synonyms: 4-(2,3-difluoro-phenyl)-1H-indole
• CAS NO: 442562-83-6
• Molecular Weight: 229.229
• Mol File: 442562-83-6.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 4-(2,3-difluoro-phenyl)-1H-indole(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(2,3-difluoro-phenyl)-1H-indole(442562-83-6)
• EPA Substance Registry System: 4-(2,3-difluoro-phenyl)-1H-indole(442562-83-6)

Safety Data

• Hazardous Substances Data: 442562-83-6(Hazardous Substances Data)

Upstream product

• 38573-88-5 1-bromo-2,3-difluorobenzene 
• 388116-27-6 indole-4-boronic acid pinacol ester 

Downstream Products

• 442563-13-5 4-(2,3-difluoro-phenyl)-1,3-dihydro-indol-2-one 

Relevant articles and documents

PYRROLO-NITROGENOUS HETEROCYCLIC DERIVATIES,THE PREPARATION AND THE PHARMCETICAL USE THEEOF

The invention provides new pyrrolo-nitrogenous heterocyclic derivatives represented by formula (I) or their salts, the preparation thereof, pharmaceutical compositions containing such derivatives and the use of such derivatives as therapeutic agents, especially as protein kinase inhibitors, wherein each substituent in formula (I) is same as defined in the description.

2-(2-OXOINDOLINE-3-YLIDENE)METHYL-5-(2-HYDROXY-3-MORPHOLIN-4-YL -PROPYL)-6,7-DIHYDRO -1H- PYRROL[3,2-C]PYRIDINE-4(5H)-ONE COMPOUNDS AND USE AS PROTEIN KINASE INHIBITORS

Pyrrolo[3,2-c]pyridine-4-one-2-indolinone compounds, especially 2-(2-oxoindoline-3-ylidene)methyl-5-(2-hydroxy-3-morpholin-4-yl-propyl)-6,7-dihyd ro-1H-pyrrol[3,2-c]pyridine-4(5H)-one compounds. Their preparation and pharmaceutical composition, and pharma

4-aryl substituted indolinones

The present invention relates to 4-arylindolinones, as well as pharmaceutical compositions thereof, capable of modulating protein kinase signal transduction in order to regulate, modulate and/or inhibit abnormal cell proliferation. The present invention also relates to methods for treating protein kinase related disorders.