442682-35-1

Basic information

• Product Name: bis(2-cyanoethyl) 4-[2-(difluoromethoxy)phenyl]-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylate
• Synonyms: bis(2-cyanoethyl) 4-[2-(difluoromethoxy)phenyl]-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylate
• CAS NO: 442682-35-1
• Molecular Weight: 445.423
• Mol File: 442682-35-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: bis(2-cyanoethyl) 4-[2-(difluoromethoxy)phenyl]-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: bis(2-cyanoethyl) 4-[2-(difluoromethoxy)phenyl]-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylate(442682-35-1)
• EPA Substance Registry System: bis(2-cyanoethyl) 4-[2-(difluoromethoxy)phenyl]-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylate(442682-35-1)

Safety Data

• Hazardous Substances Data: 442682-35-1(Hazardous Substances Data)

Upstream product

• 71653-64-0 o-difluoromethoxybenzaldehyde 
• 65193-87-5 2-cyanoethylacetoacetate 

Downstream Products

• 442682-38-4 bis[(isobutyryloxy)methyl] 4-[2-(difluoromethoxy)phenyl]-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate 
• 442682-40-8 (-)-(4R)-4-[2-(difluoromethoxy)phenyl]-5-{[(isobutyryloxy)methoxy]carbonyl}-2,6-dimethyl-1,4-dihydro-3-pyridinecarboxylic acid 
• 442682-41-9 (-)-3-[(isobutyryloxy)methyl] 5-methyl (4R)-4-[2-(difluoromethoxy)phenyl]-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylate 
• 400884-19-7 (-)-(4S)-4-[2-(difluoromethoxy)phenyl]-5-(methoxycarbonyl)-2,6-dimethyl-1,4-dihydro-3-pyridinecarboxylic acid 
• 442682-36-2 4-[2-(difluoromethoxy)phenyl]-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylic acid 

Relevant articles and documents

An efficient chemoenzymatic approach to enantiomerically pure 4-[2-(difluoromethoxy)phenyl] substituted 1,4-dihydropyridine-3,5-dicarboxylates

An efficient chemoenzymatic synthesis of (-)-3-methyl 5-(2-propoxyethyl) (4R)-4-[2-(difluoromethoxy)phenyl]-2,6-dimethyl-1,4-dihydro-3, 5-pyridinedicarboxylate has been achieved. The key step is a highly stereoselective Candida rugosa lipase (CRL)-mediate