4433-49-2

Basic information

• Product Name: Cyclohexenothiazole
• Synonyms: 4,5,6,7-tetrahydro-benzothiazole;4,5-Tetramethylen-thiazol;4,5,6,7-Tetrahydro-benzothiazol;4,5,6,7-tetrahydro-1,3-benzothiazol-2-amine hydrochloride;4,5,6,7-Tetrahydro-benzothiazol-2-ylamin,Hydrochlorid;4,5,6,7-Tetrahydro-benzothiazol-2-ylamine hydrochloride
• CAS NO: 4433-49-2
• Molecular Formula: C7H9NS
• Molecular Weight: 139.221
• Mol File: 4433-49-2.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Cyclohexenothiazole(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclohexenothiazole(4433-49-2)
• EPA Substance Registry System: Cyclohexenothiazole(4433-49-2)

Safety Data

• Hazardous Substances Data: 4433-49-2(Hazardous Substances Data)

Upstream product

• 1056477-06-5 2-bromocyclohexanone 
• 115-08-2 thiocarboxamide 
• 2933-29-1 2-Amino-4,5,6,7-tetrahydrobenzothiazole 
• 822-87-7 2-Chlorocyclohexanone 
• 89776-03-4 2,4,5,6,7,7a-hexahydro-benzothiazole 

Downstream Products

• 691883-33-7 phenyl(4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl)phosphinic chloride 

Relevant articles and documents

Tetrahydrobenzothiazol-2-acetone oxime derivative and preparation method and application thereof

The invention discloses a tetrahydrobenzothiazole-2-acetone oxime derivative, and a preparation method and application thereof. A structural formula is shown in the description. R is any one of the following radical groups: 4-methylphenyl, phenyl, 2-methylphenyl, 3-methylphenyl, 2,5-dimethylphenyl, 3,5-dimethylphenyl, 4-n-propylphenyl, 4-tert-butylphenyl, 4-methoxyphenyl, 3-methoxyphenyl, 3,4,5-trimethoxyphenyl, 3-biphenyl, 4-trifluoromethoxyphenyl, 3-fluorophenyl, 4-fluorophenyl, 4-chlorophenyl, 3-chlorophenyl, 3,5-bis(trifluoromethyl)phenyl, 3-chloro-4-methylphenyl, 3-furyl, 3-thienyl, 2-pyridyl, 4-pyridyl, 2-quinolyl, and 6-quinolyl. The tetrahydrobenzothiazol-2-acetone oxime derivative has relatively high antitumor activity and is suitable for preparing antitumor drugs. The preparationmethod of the derivative has the characteristics of cheap and readily available raw materials, short steps, and high reaction efficiency.

1,2,3-Benzothiadiazole derivatives

Novel 1,2,3-benzothiadiazole derivatives of the formula STR1 in which Het has the meanings set forth in the specification, and addition products thereof with an acid or metal salt are very effective for the control of undesired microorganisms. Novel intermediates of the formulae STR2 in which Het1 and R5 have the meanings given in the specification.

New N-aryl and N-heteroarylamide and urea derivatives as inhibitors of acyl coenzyme A: cholesterol acyl transferase

Compounds of the formula the pharmaceutically acceptable salts thereof, wherein Q and R1 are as defined below, and novel carboxylic acid and acid halide intermediates used in the synthesis of such compounds. The compounds of formula I are inhibitors of acyl coenzyme A: cholesterol acyltransferase (ACAT) and are useful as hypolipidemic and antiatherosclerosis agents.