443761-68-0Relevant articles and documents
A practical building block for the synthesis of discodermolide
Loiseleur, Olivier,Koch, Guido,Wagner, Trixie
supporting information, p. 597 - 602 (2013/09/02)
A new highly diastereoselective and practical route to the lactone 6a which is used as a key building block for the total synthesis of the microtubule-stabilizing anticancer agent discodermolide is reported. This exploits the chiral auxiliary (4R)-4-isopr