443791-75-1 Usage
Description
3-Oleoylestrone-d4, also known as 3-Oleoylestrone-2,4,16,16-d4, is an isotopically labeled research compound with the CAS number 443791-75-1. It is a derivative of oleoylestrone, a naturally occurring fatty acid ester that has been studied for its potential biological activities and applications in various fields.
Uses
Used in Research Applications:
3-Oleoylestrone-d4 is used as a research compound for studying the biological activities and mechanisms of action of oleoylestrone and its analogs. The incorporation of deuterium isotopes in the molecule allows for the investigation of its metabolic pathways, distribution, and interactions with biological targets.
Used in Pharmaceutical Industry:
3-Oleoylestrone-d4 is used as a tool in the development of new drugs and therapies targeting various diseases and conditions. Its isotopically labeled nature enables researchers to track its pharmacokinetics and pharmacodynamics, providing valuable insights into the drug's efficacy and safety.
Used in Analytical Chemistry:
3-Oleoylestrone-d4 is employed as an internal standard or reference compound in analytical techniques such as mass spectrometry and nuclear magnetic resonance (NMR) spectroscopy. Its unique isotopic signature allows for accurate quantification and identification of related compounds in complex samples.
Used in Nutritional Science:
3-Oleoylestrone-d4 can be utilized in nutritional studies to investigate the role of oleoylestrone and its derivatives in modulating appetite, energy metabolism, and other physiological processes. The isotopically labeled compound can help elucidate the mechanisms underlying these effects and guide the development of novel nutritional interventions.
Check Digit Verification of cas no
The CAS Registry Mumber 443791-75-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,4,3,7,9 and 1 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 443791-75:
(8*4)+(7*4)+(6*3)+(5*7)+(4*9)+(3*1)+(2*7)+(1*5)=171
171 % 10 = 1
So 443791-75-1 is a valid CAS Registry Number.
443791-75-1Relevant articles and documents
Microwave-assisted synthesis of deuterium labeled estrogen fatty acid esters
Kiuru, Paula S.,Waehaelae, Kristiina
, p. 54 - 60 (2007/10/03)
Deuterated analogs of estrogen fatty acid esters are needed as internal standards for isotope dilution GC/MS analyses. We have developed a rapid and efficient synthesis for 2,4,16,16-D4-estrone palmitate, stearate, oleate, linoleate, and linolenate and the corresponding 2,4,16,16,17α- D5-estradiol fatty acid 17-mono and 3,17-diesters using analogous fatty acid chlorides or fatty acid anhydrides and 4-(dimethylamino)pyridine under microwave irradiation. Chemoselective hydrolysis of fatty acid diesters was carried out by KOH in t-BuOH.
