443792-08-3Relevant articles and documents
Cardenamides from cardenolides: Cardiac and anticancer activities
Megges, Rudolf,Weiland, Juergen,Schoen, Rudolf,Repke, Heinrich,Repke, Kurt R. H.
, p. 336 - 352 (2002)
Two ways are shown to transform cardioactive cardenolides into cardenamides [17β-(5-oxo-2,5-dihydropyrrol-3-yl)-5β,14β-androstane derivatives], and their derivatives by replacement of their ring oxygen by N-R. Cardioactivity is strongly decreased by this