444606-18-2 Usage
General Description
SB-681323 is a selective and potent inhibitor of the protein kinase CK1δ, which plays a key role in regulating the circadian clock and cell cycle progression. This chemical has been studied for its potential therapeutic applications in treating sleep disorders, certain types of cancer, and neurodegenerative diseases. SB-681323 has been shown to modulate the phosphorylation of target proteins involved in these processes, and its specificity for CK1δ makes it a promising candidate for further drug development. Research on SB-681323 continues to uncover its potential uses in various medical conditions and its mechanism of action in targeting CK1δ.
Check Digit Verification of cas no
The CAS Registry Mumber 444606-18-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,4,4,6,0 and 6 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 444606-18:
(8*4)+(7*4)+(6*4)+(5*6)+(4*0)+(3*6)+(2*1)+(1*8)=142
142 % 10 = 2
So 444606-18-2 is a valid CAS Registry Number.
444606-18-2Relevant articles and documents
NOVEL PROCESS AND FORMULATIONS
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Page/Page column 99-100, (2010/11/27)
The present invention provides for a novel process of making 6-carboxylic acid derivatives of pyrido[2,3-d]pyrimidin-7-one's, as well as a novel process for making 8-(2,6-difluorophenyl)-4-(4-fluoro-2-methylphenyl)-2-{[2-hydroxy-l- (hydroxymethyl)ethyl]-amino}pyrido[2,3-d]pyrimidin-7(8H)-one, and salts thereof.
