444797-38-0

Basic information

• Product Name: 3-(3-cyclopentyloxy-4-methoxy-phenyl)-2-methyl-butyric acid ethyl ester
• Synonyms: 3-(3-cyclopentyloxy-4-methoxy-phenyl)-2-methyl-butyric acid ethyl ester
• CAS NO: 444797-38-0
• Molecular Weight: 320.429
• Mol File: 444797-38-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-(3-cyclopentyloxy-4-methoxy-phenyl)-2-methyl-butyric acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(3-cyclopentyloxy-4-methoxy-phenyl)-2-methyl-butyric acid ethyl ester(444797-38-0)
• EPA Substance Registry System: 3-(3-cyclopentyloxy-4-methoxy-phenyl)-2-methyl-butyric acid ethyl ester(444797-38-0)

Safety Data

• Hazardous Substances Data: 444797-38-0(Hazardous Substances Data)

Upstream product

• 141184-48-7 1-[3-(cyclopentyloxy)-4-methoxyphenyl]-ethanone 
• 3699-66-9 ethyl 2-diethoxyphosphorylpropionate 

Downstream Products

• 444797-39-1 3-(3-cyclopentyloxy-4-methoxy-phenyl)-2-methyl-butyric acid 

Relevant articles and documents

Synthesis and biological evaluation of imidazol-2-one and 2-cyanoiminoimidazole derivatives: novel series of PDE4 inhibitors.

This communication describes the synthesis and in vitro PDE4 inhibitory activity of a novel series of imidazol-2-one and 2-cyanoiminoimidazole derivatives. The compounds described were also tested in in vivo models to evaluate their anti-inflammatory activity after topical administration as well as their gastro-intestinal side effects. Several compounds proved to be potent PDE4 inhibitors and some 2-cyanoiminoimidazoles showed less pronounced gastro-intestinal side effects than reference compounds but maintained anti-inflammatory activity after topical administration.