444809-89-6Relevant articles and documents
Regioselective Bromine/Magnesium Exchange for the Selective Functionalization of Polyhalogenated Arenes and Heterocycles
Desaintjean, Alexandre,Haupt, Tobias,Bole, Leonie J.,Judge, Neil R.,Hevia, Eva,Knochel, Paul
supporting information, p. 1513 - 1518 (2020/11/30)
Using the bimetallic combination sBu2Mg?2 LiOR (R=2-ethylhexyl) in toluene enables efficient and regioselective Br/Mg exchanges with various dibromo-arenes and -heteroarenes under mild reaction conditions and provides bromo-substituted magnesiu
Expedient synthesis of xanthones and multi-functionalized chromones from 1,1-diacyl cyclopropanes
French, Sarah A.,Clark, Mitchell R.,Smith, Robert J.,Brind, Thomasin,Hawkins, Bill C.
supporting information, p. 5340 - 5350 (2018/04/19)
We report the rapid synthesis of various cycloheptane-fused chromones and an oxepine fused flavone in 5 steps from the corresponding 2-hydroxy acetophenone. Furthermore, we describe the synthesis of xanthones, in moderate to good yield, from 2,3-disubstit
Synthesis of Allyl- and Prenylcoumarins via Microwave-Promoted Tandem Claisen Rearrangement/Wittig Olefination
Schmidt, Bernd,Riemer, Martin
supporting information, p. 141 - 149 (2015/12/26)
Allyl, dimethylallyl, crotyl, and prenyl ethers of various aromatic ortho-hydroxy carbonyl compounds undergo a tandem sequence of Claisen rearrangement, carbonyl olefination, and cyclization upon microwave irradiation in the presence of a stabilized ylide. The products are multiply substituted 6- or 8-allylated or prenylated coumarins (2H-chromen-2-ones).
