445490-70-0

Basic information

• Product Name: 3-(5-{2-[N-(4,5-Dihydro-1H-imidazol-2-yl)-aminooxy]-ethoxy}-indol-1-yl)-3-phenyl-propionic acid ethyl ester
• Synonyms: 3-(5-{2-[N-(4,5-Dihydro-1H-imidazol-2-yl)-aminooxy]-ethoxy}-indol-1-yl)-3-phenyl-propionic acid ethyl ester
• CAS NO: 445490-70-0
• Molecular Weight: 436.511
• Mol File: 445490-70-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3-(5-{2-[N-(4,5-Dihydro-1H-imidazol-2-yl)-aminooxy]-ethoxy}-indol-1-yl)-3-phenyl-propionic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(5-{2-[N-(4,5-Dihydro-1H-imidazol-2-yl)-aminooxy]-ethoxy}-indol-1-yl)-3-phenyl-propionic acid ethyl ester(445490-70-0)
• EPA Substance Registry System: 3-(5-{2-[N-(4,5-Dihydro-1H-imidazol-2-yl)-aminooxy]-ethoxy}-indol-1-yl)-3-phenyl-propionic acid ethyl ester(445490-70-0)

Safety Data

• Hazardous Substances Data: 445490-70-0(Hazardous Substances Data)

Upstream product

• 445490-69-7 3-[5-(2-aminooxy-ethoxy)-indol-1yl]-3-phenyl-propionic acid ethyl ester 
• 2581-34-2 3-methyl-4-nitrophenol 
• 445490-68-6 3-{5-[2-(1,3-dioxo-1,3-dihydro-isoindol-2-yloxy)-ethoxy]-indol-1-yl}-3-phenyl-propionic acid ethyl ester 
• 445490-66-4 3-[-5-(2-benzyloxy-ethoxy)-indol-1-yl]-3-phenyl-acrylic acid ethyl ester 
• 445490-67-5 3-[5-(2-Hydroxy-ethoxy)-indol-1-yl]-3-phenyl-propionic acid ethyl ester 
• 132369-02-9 2-(3,5-dimethylpyrazolyl)-4,5-dihydroimidazole hydrobromide 
• 445490-65-3 5-(2-benzyloxyethoxy)-1H-indole 
• 193358-15-5 2-methyl-1-nitro-4-[2-(phenylmethoxy)ethoxy]benzene 

Relevant articles and documents

Non-peptidic αvβ3 antagonists containing indol-1-yl propionic acids

We describe the synthesis and structure/activity relationship of RGD mimetics that are potent inhibitors of the integrin αvβ 3. Indol-1-yl propionic acids containing a variety of basic moieties at the 5-position, as well as substitutions alpha and beta to the carboxy terminus were synthesized and evaluated. Novel compounds with improved potency have been identified.