4458-18-8 Usage
General Description
2,4-DIAMINO-5-AMINOMETHYL-PYRIMIDINE is a chemical compound with the molecular formula C6H10N4. It is a pyrimidine derivative that is used in the production of pharmaceuticals and as a building block for various organic synthesis reactions. 2,4-DIAMINO-5-AMINOMETHYL-PYRIMIDINE is a key intermediate in the synthesis of nucleotides, which are essential for DNA and RNA production. It is also used in the production of antiviral and anticancer drugs. 2,4-DIAMINO-5-AMINOMETHYL-PYRIMIDINE has also shown potential as an anti-inflammatory agent. Due to its versatile applications in the pharmaceutical industry, this compound is of great interest to researchers and chemists.
Check Digit Verification of cas no
The CAS Registry Mumber 4458-18-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,4,5 and 8 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 4458-18:
(6*4)+(5*4)+(4*5)+(3*8)+(2*1)+(1*8)=98
98 % 10 = 8
So 4458-18-8 is a valid CAS Registry Number.
InChI:InChI=1/C5H9N5/c6-1-3-2-9-5(8)10-4(3)7/h2H,1,6H2,(H4,7,8,9,10)
4458-18-8Relevant articles and documents
Lewis acid-catalyzed synthesis of 4-aminopyrimidines: A scalable industrial process
Letinois, Ulla,Schuetz, Jan,Haerter, Ralph,Stoll, Rinke,Huffschmidt, Florian,Bonrath, Werner,Karge, Reinhard
supporting information, p. 427 - 431 (2013/05/09)
Pyrimidine synthesis starting from acrylonitrile has been known since the 1960s. The new Lewis acid-catalyzed condensation reaction allows the synthesis of 4-aminopyrimidines starting from the easily accessible chemical acrylonitrile without the need for carcinogenic chemicals and costly derivatization in up to 90% yield. The method is versatile and applicable for industrial-scale synthesis of biologically relevant substances such as vitamin B1 and trimethoprim.
