446-22-0 Usage
Description
2-Fluoropropiophenone, with the CAS number 446-22-0, is a pale yellow oil compound that is primarily utilized in the field of organic synthesis. It is known for its unique chemical properties that make it a valuable component in various chemical reactions and processes.
Uses
Used in Organic Synthesis:
2-Fluoropropiophenone is used as a key intermediate in the synthesis of various organic compounds. Its chemical properties, including its pale yellow oil consistency, make it a versatile building block for creating a wide range of molecules with different applications across various industries.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2-Fluoropropiophenone is used as a starting material for the development of new drugs. Its unique chemical structure allows for the creation of novel molecules with potential therapeutic properties, contributing to the advancement of medical treatments.
Used in Chemical Research:
2-Fluoropropiophenone is also employed in chemical research as a tool to study various reaction mechanisms and to develop new synthetic methods. Its properties make it an ideal candidate for exploring new pathways and techniques in organic chemistry.
Used in Material Science:
In the field of material science, 2-Fluoropropiophenone is used as a component in the development of new materials with specific properties. Its chemical structure can be manipulated to create materials with tailored characteristics, such as improved stability or enhanced reactivity.
Check Digit Verification of cas no
The CAS Registry Mumber 446-22-0 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,4 and 6 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 446-22:
(5*4)+(4*4)+(3*6)+(2*2)+(1*2)=60
60 % 10 = 0
So 446-22-0 is a valid CAS Registry Number.
446-22-0Relevant articles and documents
Cobalt-Catalyzed Migrational Isomerization of Styrenes
Zhao, Jiajin,Cheng, Biao,Chen, Chenhui,Lu, Zhan
supporting information, p. 837 - 841 (2020/01/31)
An efficient cobalt-catalyzed migrational isomerization of styrenes was developed using the thiazoline iminopyridine (TIP) ligand. This reaction is operationally simple and atom-economical using readily available starting materials to access trisubstituted alkenes. Even when using a 0.1 mol % catalyst loading, the reaction could be conducted in neat and completed in 1 h with excellent conversion and high E stereoselectivity.
Direct conversion of allyl arenes to aryl ethylketones via a TBHP-mediated palladium-catalyzed tandem isomerization-Wacker oxidation of terminal alkenes
Zhao, Jinwu,Liu, Li,Xiang, Shijian,Liu, Qiang,Chen, Huoji
supporting information, p. 5613 - 5616 (2015/05/27)
A TBHP-mediated palladium-catalyzed tandem isomerization-Wacker oxidation of terminal alkenes was developed. This methodology provides a new efficient and simple route for conversion of a range of allyl arenes directly into aryl ethylketones in good yields with high chemoselectivity.
A facile synthesis of α-fluoro ketones catalyzed by [Cp*IrCl2]2
Ahlsten, Nanna,Bartoszewicz, Agnieszka,Agrawal, Santosh,Martin-Matute, Belen
, p. 2600 - 2608 (2011/10/02)
Allylic alcohols are isomerized into enolates (enols) by [Cp*IrCl2]2. The enolates react with Selectfluor present in the reaction media. This method produces α-fluoro ketones as single constitutional isomers in high yields. Georg Thieme Verlag Stuttgart. New York.
