446-32-2 Usage
Description
2-Amino-4-fluorobenzoic acid is an organic compound characterized by its white to light yellow crystal powder appearance. It is known for its unique chemical properties, which make it a valuable component in various applications across different industries.
Uses
Used in Organic Synthesis:
2-Amino-4-fluorobenzoic acid is used as a key intermediate in the synthesis of various organic compounds. Its unique structure and functional groups allow it to participate in a range of chemical reactions, making it a versatile building block for the creation of new molecules with potential applications in pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2-Amino-4-fluorobenzoic acid is utilized as a starting material for the development of new drugs. Its specific properties enable it to be incorporated into the molecular structures of potential therapeutic agents, targeting a variety of medical conditions.
Used in Agrochemical Industry:
2-Amino-4-fluorobenzoic acid also finds application in the agrochemical industry, where it is used as a precursor for the synthesis of various pesticides and other crop protection agents. Its unique chemical properties allow for the development of novel compounds with improved efficacy and selectivity.
Used in Research and Development:
In the field of research and development, 2-Amino-4-fluorobenzoic acid serves as an important compound for studying various chemical reactions and mechanisms. Its unique structure and properties make it an ideal candidate for exploring new reaction pathways and understanding the underlying chemistry involved.
Check Digit Verification of cas no
The CAS Registry Mumber 446-32-2 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,4 and 6 respectively; the second part has 2 digits, 3 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 446-32:
(5*4)+(4*4)+(3*6)+(2*3)+(1*2)=62
62 % 10 = 2
So 446-32-2 is a valid CAS Registry Number.
InChI:InChI=1/C6H3F2NO2/c7-4-1-2-6(9(10)11)5(8)3-4/h1-3H
446-32-2Relevant articles and documents
Preparation method of 2-amino-4-fluorobenzoic acid
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, (2021/08/28)
The invention relates to a preparation method of 2-amino-4-fluorobenzoic acid, which comprises the following steps: by taking cheap and easily available 4-fluorobenzyl alcohol as a raw material, firstly carrying out nitration reaction to obtain a nitro substitute, then carrying out oxidation reaction on the nitro substitute to obtain benzoic acid oxide, and finally carrying out reduction reaction on the benzoic acid oxide to finally obtain 2-amino-4-fluorobenzoic acid which is high in purity and high in yield. The preparation method disclosed by the invention has the characteristics of cheap and easily available raw materials, short reaction route, conventional reaction, mild reaction conditions, high yield and easiness in industrial production.
Selenium-catalyzed intramolecular atom- And redox-economical transformation ofo-nitrotoluenes into anthranilic acids
Jiang, Xuefeng,Li, Yiming,Lin, Zhenyang,Wang, Yuhong,Yang, Tilong
supporting information, p. 2986 - 2991 (2021/05/05)
Anthranilic acids (AAs) are significant basic chemicals used in pharmaceuticals, agrochemicals, dyes, fragrances,etc. Superfluous steps are always involved in obtaining AAs. Herein, we demonstrate a straightforward strategy to transform abundanto-nitrotoluenes into biologically and pharmaceutically significant AAs without any extra reductants, oxidants and protecting groups. Various sensitive groups, such as halogens, sulfide, aldehyde, pyridines, quinolines,etc., can be tolerated in this transformation. A hundred-gram-scale operation is realized efficiently with almost quantitative selenium recycling. Further mechanistic studies and DFT calculations disclosed the proposed atom-exchange processes and the key roles of the selenium species.
ARYLQUINAZOLINES
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Paragraph 0343, (2016/04/19)
The invention relates to novel compounds of the formula (I) which can be used for the inhibition of serine-threonine protein kinases and for the sensitisation of cancer cells to anticancer agents and/or ionising radiation.