4461-27-2

Basic information

• Product Name: Benzeneacetyl isocyanate
• CAS NO: 4461-27-2
• Molecular Formula: C9H7NO2
• Molecular Weight: 161.16
• Mol File: 4461-27-2.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Benzeneacetyl isocyanate(CAS DataBase Reference)
• NIST Chemistry Reference: Benzeneacetyl isocyanate(4461-27-2)
• EPA Substance Registry System: Benzeneacetyl isocyanate(4461-27-2)

Safety Data

• Hazardous Substances Data: 4461-27-2(Hazardous Substances Data)

Upstream product

• 17384-58-6 2-benzylidene-oxazolidine-4,5-dione 
• 79-37-8 oxalyl dichloride 
• 95-50-1 1,2-dichloro-benzene 
• 103-80-0 phenylacetyl chloride 
• 103-81-1 Benzeneacetamide 
• 1118-02-1 trimethylsilyl isocyanate 
• 3315-16-0 silver cyanate 

Downstream Products

• 741716-56-3 t-butyl 2-methylene-3-phenyl-3-phenylacetylaminocarbonyloxypropanoate 
• 26172-73-6 dimethyl 2-benzylfuran-3,4-dicarboxylate 
• 89873-79-0 2,3-dimethyl-4,6,7-triphenyl-4H-pyrazolo<5,1-c><1,4>oxazine 
• 78707-34-3 N-Phenylacetyl-N'-<3,4-dichlor-phenyl>-harnstoff 
• 873988-67-1 1-Phenylacetyl-biuret 
• 69486-46-0 1-(N-phenylacetyl-carbamoyl)-2-cyanoaziridine 

Relevant articles and documents

NOVEL PYRIDINE DERIVATIVE AND PYRIMIDINE DERIVATIVE

-

Carbamoyloxy derivatives of mutiline and their use as antibacterials

PCT No. PCT/EP96/05874 Sec. 371 Date Dec. 4, 1998 Sec. 102(e) Date Dec. 4, 1998 PCT Filed Dec. 19, 1996 PCT Pub. No. WO97/25309 PCT Pub. Date Jul. 17, 1997Derivatives of mutiline of formula (1A) and pharmaceutically acceptable salts and derivatives thereof, in which R1 is ethyl or vinyl, Y is a carbamoyloxy group, in which the N-atom is unsubstituted, or mono- or di-substituted, are useful in the treatment of bacterial infections.

Process for the preparation of acyl isocyanates

The invention concerns a process for the preparation of acyl isocyanates which consists of reacting oxalyl chloride with a salt selected from the group consisting of hydrohalides and sulphates of carboxamides and/or carbamates, unsubstituted on nitrogen, then heating the reaction mixture at a temperature between 30° and 150° C. The process is suitable for preparation of acyl isocyanates with excellent yields in easy to control operational conditions.