446253-67-4

Basic information

• Product Name: (2R)-2-azido-N-benzyl-3-phenylpropionamide
• Synonyms: (2R)-2-azido-N-benzyl-3-phenylpropionamide
• CAS NO: 446253-67-4
• Molecular Weight: 280.329
• Mol File: 446253-67-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (2R)-2-azido-N-benzyl-3-phenylpropionamide(CAS DataBase Reference)
• NIST Chemistry Reference: (2R)-2-azido-N-benzyl-3-phenylpropionamide(446253-67-4)
• EPA Substance Registry System: (2R)-2-azido-N-benzyl-3-phenylpropionamide(446253-67-4)

Safety Data

• Hazardous Substances Data: 446253-67-4(Hazardous Substances Data)

Upstream product

• 673-06-3 D-(R)-phenylalanine 
• 237057-77-1 (S)-N-benzyl-2-hydroxy-3-phenylpropionamide 
• 122-78-1 phenylacetaldehyde 
• 88333-03-3 Benzyl isocyanide 
• 946534-43-6 C₁₇H₁₉NO₃SO 
• 118460-00-7 (R)-2-azido-3-phenylpropionic acid 
• 100-46-9 benzylamine 
• 215593-50-3 acetic acid 1-benzylcarbamoyl-2-phenylethyl ester 

Downstream Products

• 72244-52-1 (R)-N-benzyl 2-amino-3-phenylpropionamide 

Relevant articles and documents

Studies on the application of the Passerini reaction and enzymatic procedures to the synthesis of tripeptide mimetics

A new, efficient method for the multicomponent synthesis of tripeptide mimetics is presented. Simple, chemoenzymatic transformations of Passerini reaction products enable the introduction of varied amino acid moieties into the tripeptide scaffold, with co

Staudinger ligation of α-azido acids retains stereochemistry

The Staudinger ligation of peptides with a C-terminal phosphinothioester and N-terminal azide is an emerging method in protein chemistry. Here, the first Staudinger ligations of nonglycyl azides are reported and shown to proceed both in nearly quantitative yield and with no detectable effect on the stereochemistry at the α-carbon of the azide. These results demonstrate further the potential of the Staudinger ligation as a general method for the total synthesis of proteins from peptide fragments.