446302-83-6 Usage
General Description
1-Benzyl-3-phenylpiperidin-4-one, also known as BZP, is a chemical compound that belongs to the piperidine class. It is a psychoactive drug with stimulant effects that is often used as a recreational drug. BZP is structurally similar to amphetamine and acts as a serotonin-norepinephrine-dopamine reuptake inhibitor. It is known to produce effects such as increased energy, alertness, and euphoria, but can also cause adverse effects such as nausea, anxiety, and insomnia. BZP and its analogues have been banned in many countries due to their potential for abuse and adverse health effects, and are classified as controlled substances in some jurisdictions.
Check Digit Verification of cas no
The CAS Registry Mumber 446302-83-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,4,6,3,0 and 2 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 446302-83:
(8*4)+(7*4)+(6*6)+(5*3)+(4*0)+(3*2)+(2*8)+(1*3)=136
136 % 10 = 6
So 446302-83-6 is a valid CAS Registry Number.
InChI:InChI=1/C18H19NO/c20-18-11-12-19(13-15-7-3-1-4-8-15)14-17(18)16-9-5-2-6-10-16/h1-10,17H,11-14H2
446302-83-6Relevant articles and documents
Development of κ opioid receptor agonists by focusing on phenyl substituents of 4-dimethylamino-3-phenylpiperidine derivatives: Structure-activity relationship study of matrine type alkaloids
Teramoto, Hiroyoshi,Yamauchi, Takayasu,Sasaki, Shigeru,Higashiyama, Kimio
, p. 420 - 431 (2016/06/01)
A series of new κ opioid receptor (KOR) agonists were developed from the lead compound 4-dimethylamino-1-pentanoylpiperidine (3), a matrine-type alkaloid. Derivatives of 3 were synthesized with a variety of phenyl substituents and evaluated for their anti
Synthesis of 3-phenyl-4-piperidones from acetophenone by shapiro and azamichael reactions and their further derivatization
Rosiak, Anna,Hoenke, Christoph,Christoffers, Jens
, p. 4376 - 4382 (2008/04/13)
The Shapiro reaction of acetophenone is the key in a convenient three-step access to a divinyl ketone which is further transformed by double aza-Michael reactions with primary amines into N-substituted 3-phenyl-4-piperidones. In the case of N-benzyl and N