448927-81-9

Basic information

• Product Name: (R)-N²-Methyl-3-[(R)-2-methylamino-3-((R)-1-phenyl-ethylamino)-propyldisulfanyl]-N¹-((R)-1-phenyl-ethyl)-propane-1,2-diamine
• CAS NO: 448927-81-9
• Molecular Weight: 446.725
• Mol File: 448927-81-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R)-N²-Methyl-3-[(R)-2-methylamino-3-((R)-1-phenyl-ethylamino)-propyldisulfanyl]-N¹-((R)-1-phenyl-ethyl)-propane-1,2-diamine(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-N²-Methyl-3-[(R)-2-methylamino-3-((R)-1-phenyl-ethylamino)-propyldisulfanyl]-N¹-((R)-1-phenyl-ethyl)-propane-1,2-diamine(448927-81-9)
• EPA Substance Registry System: (R)-N²-Methyl-3-[(R)-2-methylamino-3-((R)-1-phenyl-ethylamino)-propyldisulfanyl]-N¹-((R)-1-phenyl-ethyl)-propane-1,2-diamine(448927-81-9)

Safety Data

• Hazardous Substances Data: 448927-81-9(Hazardous Substances Data)

Upstream product

• 56-89-3 L-cystine 
• 448927-71-7 [(R)-2-[(R)-2-Ethoxycarbonylamino-2-((R)-1-phenyl-ethylcarbamoyl)-ethyldisulfanyl]-1-((R)-1-phenyl-ethylcarbamoyl)-ethyl]-carbamic acid ethyl ester 
• 19887-39-9 (R,R)-N,N'-diethoxycarbonyl-3,3'-dithiobis(2-aminopropionic acid) 

Relevant articles and documents

Synthesis of new chiral imidazolidine disulfides derived from L-cystine and their application in the enantioselective addition of diethylzinc to aldehydes

Several chiral imidazolidine disulfides 4a-d derived from L-cystine have been synthesized. These ligands have been applied as chiral catalysts in the asymmetric addition of diethylzinc to aldehydes. The best results were obtained by employing 5 mol% of imidazolidine disulfide 4a, and chiral secondary alcohols were obtained in up to 91% e.e.