449143-75-3

Basic information

• Product Name: (S)-3-[(1S,2R,4R)-4-[(benzyloxy)methoxy]-1-(methylsulfanyl)-2,4-diphenylbutyl]-4-isopropyl-5,5-diphenyloxazolidin-2-one
• Synonyms: (S)-3-[(1S,2R,4R)-4-[(benzyloxy)methoxy]-1-(methylsulfanyl)-2,4-diphenylbutyl]-4-isopropyl-5,5-diphenyloxazolidin-2-one
• CAS NO: 449143-75-3
• Molecular Weight: 671.901
• Mol File: 449143-75-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-3-[(1S,2R,4R)-4-[(benzyloxy)methoxy]-1-(methylsulfanyl)-2,4-diphenylbutyl]-4-isopropyl-5,5-diphenyloxazolidin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-3-[(1S,2R,4R)-4-[(benzyloxy)methoxy]-1-(methylsulfanyl)-2,4-diphenylbutyl]-4-isopropyl-5,5-diphenyloxazolidin-2-one(449143-75-3)
• EPA Substance Registry System: (S)-3-[(1S,2R,4R)-4-[(benzyloxy)methoxy]-1-(methylsulfanyl)-2,4-diphenylbutyl]-4-isopropyl-5,5-diphenyloxazolidin-2-one(449143-75-3)

Safety Data

• Hazardous Substances Data: 449143-75-3(Hazardous Substances Data)

Upstream product

• 3587-60-8 Benzyloxymethyl chloride 

Downstream Products

• 184346-45-0 (S)-5,5-Diphenyl-4-isopropyl-1,3-oxazolidin-2-one 

Relevant articles and documents

Conjugate addition of lithiated (S)-4-isopropyl-3-[(methylthio)methyl]-5,5-diphenyloxazolidin-2-one to cinnamoyl derivatives: Preparation of enantiomerically pure 1,4-diols

The Li derivative of (S)-4-isopropyl-3-[(methylthlio)methyl]-5,5-diphenyloxazolidin-2-one (Li-2; synthetically equivalent to a chiral formyl anion) adds to enones and enoates in a 1,4-fashion. Best results are obtained with 1,3-diarylpropenones (chalcones