4510-08-1 Usage
Description
H-MET-NH2, also known as N-methyl-L-methionine, is an amino acid amide derived from L-methionine, where the carboxy OH group is replaced by an NH2 group. This modification gives H-MET-NH2 unique properties that can be utilized in various applications.
Uses
Used in Pharmaceutical Industry:
H-MET-NH2 is used as a pharmaceutical compound for its potential therapeutic applications. The replacement of the carboxy OH group with an NH2 group in L-methionine may result in altered biological activities, making it a candidate for the development of new drugs or drug delivery systems.
Used in Chemical Synthesis:
H-MET-NH2 can be used as a building block in the synthesis of various organic compounds, including pharmaceuticals, agrochemicals, and other specialty chemicals. Its unique structure may provide new synthetic pathways and opportunities for the development of novel molecules with specific properties.
Used in Research and Development:
H-MET-NH2 can be employed as a research tool in the study of protein structure, function, and interactions. The modified methionine residue can be used to investigate the effects of amino acid substitutions on protein stability, folding, and activity, contributing to a better understanding of protein biology and the development of targeted therapies.
Used in Analytical Chemistry:
H-MET-NH2 can be utilized as a reference compound or internal standard in analytical chemistry, particularly in the analysis of amino acids and peptides. Its unique properties may help improve the accuracy and precision of analytical methods, leading to better quantification and identification of biological molecules.
Check Digit Verification of cas no
The CAS Registry Mumber 4510-08-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,5,1 and 0 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 4510-08:
(6*4)+(5*5)+(4*1)+(3*0)+(2*0)+(1*8)=61
61 % 10 = 1
So 4510-08-1 is a valid CAS Registry Number.
4510-08-1Relevant articles and documents
Photooxidation of Methionine Derivatives by the 4-Carboxybenzophenone Triplet State in Aqueous Solution. Intracomplex Proton Transfer Involving the Amino Group
Hug, Gordon L.,Bobrowski, Krzysztof,Kozubek, Halina,Marciniak, Bronislaw
, p. 785 - 796 (2007/10/03)
Oxidation of the triplet state of 4-carboxybenzophenone (CB) by a series of five substituted methionines and three methionine-containing dipeptides was monitored under laser flash photolysis conditions in aqueous solution. Spectral resolution techniques were employed to follow the concentration profiles of the intermediates formed from the quenching events. From these concentration profiles, quantum yields for the intermediates were determined. Branching ratios were evaluated for the decay of the charge-transfer complex by the competing processes of back electron transfer, proton transfer and escape of radical ions. The relative prominence of these processes was discussed in terms of the proton-transfer tendencies of the nominal sulfur-radical-cationic species. A systematic decrease was observed in the quantum yields for the escape of radical ions along with a correlated increase in the proton-transfer yields. The enhanced propensity of the sulfur radical cations to deprotonate is due to deprotonation at the carbons adjacent to the sulfur-cationic site and at the unsubstituted amino groups when present. This scheme was supported by an observed decrease in the yields of dimeric sulfur radical cations with an increase in the electron-withdrawing abilities of the substituents, making the radical-cationic species stronger acids. The involvement of protons on the amino groups was implicated by the correlation of the quantum yields of ketyl radical formation in the photo-chemistry experiments with the rate constants for the reaction of the CB radical anion with the sulfur-containing substrates in pulse radiolysis experiments.
