452088-49-2

Basic information

• Product Name: Benzoic acid, 4-[(3-methylphenyl)amino]-3-nitro-
• Synonyms: 3-Nitro-4-(3-toluidino)benzoic acid;3-NITRO-4-(M-TOLYLAMINO)BENZOIC ACID;Benzoic acid, 4-[(3-methylphenyl)amino]-3-nitro-
• CAS NO: 452088-49-2
• Molecular Formula: C14H12N2O4
• Molecular Weight: 272.26
• Mol File: 452088-49-2.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 449.8±45.0 °C(Predicted)
• Appearance: /
• Density: 1.388±0.06 g/cm3(Predicted)
• PKA: 3.98±0.10(Predicted)
• CAS DataBase Reference: Benzoic acid, 4-[(3-methylphenyl)amino]-3-nitro-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 4-[(3-methylphenyl)amino]-3-nitro-(452088-49-2)
• EPA Substance Registry System: Benzoic acid, 4-[(3-methylphenyl)amino]-3-nitro-(452088-49-2)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 452088-49-2(Hazardous Substances Data)

Upstream product

• 453-71-4 3-nitro-4-fluorobenzoic acid 
• 108-44-1 1-amino-3-methylbenzene 

Relevant articles and documents

Structure-activity relationship studies and biological characterization of human NAD+-dependent 15-hydroxyprostaglandin dehydrogenase inhibitors

The structure-activity relationship (SAR) study of two chemotypes identified as inhibitors of the human NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (HPGD, 15-PGDH) was conducted. Top compounds from both series displayed potent inhibition (IC50 2 production in A549 lung cancer and LNCaP prostate cancer cells.