452322-67-7

Basic information

• Product Name: TDP-L-mycarose
• CAS NO: 452322-67-7
• Molecular Weight: 546.362
• Mol File: 452322-67-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: TDP-L-mycarose(CAS DataBase Reference)
• NIST Chemistry Reference: TDP-L-mycarose(452322-67-7)
• EPA Substance Registry System: TDP-L-mycarose(452322-67-7)

Safety Data

• Hazardous Substances Data: 452322-67-7(Hazardous Substances Data)

Upstream product

• 18424-67-4 methyl 2,6-dideoxy-3-C-methyl-α-L-ribo-hexopyranoside 
• 18423-82-0 2,4,6-trideoxy-3-methyl-α,β-L-ribo-hexopyranose 
• 59-56-3 α-D-glucopyranosyl-1-phosphate 
• 50-89-5 thymidine 

Relevant articles and documents

A two-stage one-pot enzymatic synthesis of TDP-L-mycarose from thymidine and glucose-1-phosphate

This report describes a procedure combining six enzymes native to Escherichia coli or Salmonella typhi, such as thymidine kinase (TK), thymidylate kinase (TMK), nucleoside diphosphate kinase (NDK), pyruvate kinase (PK; for ATP regeneration), TDP-glucose synthetase (RfbA), and TDP-glucose 4,6-dehydratase (RfbB), with five enzymes from Streptomyces fradiae, such as TylX3, TylC1, TylC3, TylK, and TylC2, that resulted in the biosynthesis of TDP-l-mycarose from glucose-1-phosphate and thymidine. This two-stage one-pot approach can be readily applied to the synthesis of other unusual sugars. Copyright