452914-21-5

Basic information

• Product Name: 2-(4-butoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
• Synonyms: 2-(4-butoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
• CAS NO: 452914-21-5
• Molecular Weight: 276.184
• Mol File: 452914-21-5.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 367.4±25.0 °C(Predicted)
• Density: 0.99±0.1 g/cm3(Predicted)
• CAS DataBase Reference: 2-(4-butoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-butoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane(452914-21-5)
• EPA Substance Registry System: 2-(4-butoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane(452914-21-5)

Safety Data

• Hazardous Substances Data: 452914-21-5(Hazardous Substances Data)

Usage

Type of compound

boron-containing compound

Classification

boronic ester

Structure

contains a boron atom attached to two oxygen atoms and an alkyl group

Uses

often used as a reagent in organic synthesis, particularly in the formation of carbon-carbon and carbon-heteroatom bonds

Applications

valuable in the construction of complex organic molecules, particularly in the pharmaceutical industry

Known for

stability and versatility, making it a popular choice for chemists working on the synthesis of new drugs and materials.

Upstream product

• 109-65-9 1-bromo-butane 
• 269409-70-3 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol 
• 73183-34-3 bis(pinacol)diborane 
• 33863-86-4 4-(n-butyloxy)benzoyl chloride 
• 96693-04-8 1-(n-butoxy)-4-iodobenzene 
• 39969-57-8 1-bromo-4-butoxybenzene 
• 106-41-2 4-bromo-phenol 

Downstream Products

• 1206159-50-3 5-(butoxymethyl)-2-(4-butoxyphenyl)pyridine 
• 1415309-79-3 C₁₄H₁₇N₃O₂ 

Relevant articles and documents

Controlling Mirror Symmetry Breaking and Network Formation in Liquid Crystalline Cubic, Isotropic Liquid and Crystalline Phases of Benzil-Based Polycatenars

Spontaneous development of chirality in systems composed of achiral molecules is important for new routes to asymmetric synthesis, chiral superstructures and materials, as well as for the understanding of the mechanisms of emergence of prebiotic chirality. Herein, it is shown that the 4,4′-diphenylbenzil unit is a universal transiently chiral bent building block for the design of multi-chained (polycatenar) rod-like molecules capable of forming a wide variety of helically twisted network structures in the liquid, the liquid crystalline (LC) and the crystalline state. Single polar substituents at the apex of tricatenar molecules support the formation of the achiral (racemic) cubic double network phase with Ia (Formula presented.) d symmetry and relatively small twist along the networks. The combination of an alkyl chain with fluorine substitution leads to the homogeneously chiral triple network phase with I23 space group, and in addition, provides a mirror symmetry broken liquid. Replacing F by Cl or Br further increases the twist, leading to a short pitch double gyroid Ia (Formula presented.) d phase, which is achiral again. The effects of the structural variations on the network structures, either leading to achiral phases or chiral conglomerates are analyzed.

BIPHENYL COMPOUND AS CCR2/CCR5 RECEPTOR ANTAGONIST

Provided is a CCR2/CCR5 receptor antagonist and the use thereof in the preparation of a drug for treating diseases associated with the CCR2/CCR5. In particular, disclosed are a compound represented by formula (I) and a pharmaceutically acceptable salt thereof

NOVEL COELENTERAZINE COMPOUNDS AND USES THEREOF

There is provided a series of coelenterazine (CTZ) derivatives as a substrate with high luminescence intensity, which is optimal for maximum luminescence wavelengths at both 400 nm (blue-shifted RLuc luminescence system) and 500 nm (ALuc luminescence system) for bioassays which is more sensitive than known techniques. The novel CTZ derivatives are compounds in which a specific position(s) of the CTZ is/are substituted with a specific substituent(s) as shown, for example, by the Formula [I], and has a higher luminescence intensity than known CTZ derivatives in blue-shifted RLuc luminescence system or ALuc luminescence system.