455267-29-5

Basic information

• Product Name: TERT-BUTYL 4-(1-AMINOETHYL)PIPERIDINE-1-CARBOXYLATE
• Synonyms: TERT-BUTYL 4-(1-AMINOETHYL)PIPERIDINE-1-CARBOXYLATE;1-Boc-4-(1-aMinoethyl)-piperidine;4-(1-Amino-ethyl)-piperidine-1-carboxylic acid tert-butyl ester;4-(1-Aminoethyl)-1-piperidinecarboxylic acid 1,1-dimethylethyl ester;(S)-tert-butyl 4-(1-aminoethyl)piperidine-1-carboxylate;4-(1-aminoethyl)-1-Piperidine carbocylic acid 1,1-dimethylethyl ester;1-Piperidinecarboxylicacid,4-(1-aminoethyl)-,1,1-dimethylethylester;tert-Butyl 4-(1-aminoethyl)
• CAS NO: 455267-29-5
• Molecular Formula: C₁₂H₂₄N₂O₂
• Molecular Weight: 228.33116
• Mol File: 455267-29-5.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• CAS DataBase Reference: TERT-BUTYL 4-(1-AMINOETHYL)PIPERIDINE-1-CARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: TERT-BUTYL 4-(1-AMINOETHYL)PIPERIDINE-1-CARBOXYLATE(455267-29-5)
• EPA Substance Registry System: TERT-BUTYL 4-(1-AMINOETHYL)PIPERIDINE-1-CARBOXYLATE(455267-29-5)

Safety Data

• Hazardous Substances Data: 455267-29-5(Hazardous Substances Data)

Usage

General Description

TERT-BUTYL 4-(1-AMINOETHYL)PIPERIDINE-1-CARBOXYLATE is a chemical compound with a molecular formula C13H24N2O2. It is a tert-butyl ester derivative of piperidine carboxylic acid and contains an aminoethyl group. TERT-BUTYL 4-(1-AMINOETHYL)PIPERIDINE-1-CARBOXYLATE has potential applications in medicinal chemistry, particularly for the synthesis of pharmaceuticals and other bioactive compounds. It may be used as a building block in the creation of drugs or in research related to neurotransmitters and receptors, due to its structural similarity to neurotransmitters like dopamine and serotonin. Additionally, it could be utilized in the development of new chemical entities for various biological targets.

Upstream product

• 7440-02-0 nickel 
• 206989-61-9 4-acetyl-1-(t-butoxycarbonyl)piperidine 
• 24424-99-5 di-tert-butyl dicarbonate 
• 30818-11-2 1-(4-piperidinyl)ethanone 
• 1450658-46-4 tert-butyl 4-((S)-1-(1,1-dimethylethylsulfinamido)ethyl)piperidine-1-carboxylate 
• 137076-22-3 tert butyl 4-formylpiperidine-1-carboxylate 
• 1097880-26-6 tert-butyl 4-[(E)-{[(S)-2-methylpropane-2-sulfinyl]imino}methyl]piperidine-1-carboxylate 
• 139290-70-3 tert-butyl 4-(methoxy(methyl)carbamoyl)piperidine-1-carboxylate 
• 84358-13-4 N-[(tert-butoxy)carbonyl]piperidine-4-carboxylic acid 
• 148148-48-5 4-(N-methoxy-N-methyl-carbamoyl)-piperidine-1-carboxylic acid benzyl ester 
• 160809-34-7 4-acetyl-piperidine-1-carboxylic acid benzyl ester 

Downstream Products

• 1036027-89-0 C₈H₈O₃*C₁₂H₂₄N₂O₂ 
• 1036027-88-9 C₈H₈O₃*C₁₂H₂₄N₂O₂ 
• 1428582-26-6 3-(cyclopropylmethoxy)-5-methoxy-N-(1-(piperidin-4-yl)ethyl)benzamide 2,2,2-trifluoroacetate 
• 1443004-98-5 N-(1-(1-(4-chloro-1,3,5-triazin-2-yl)piperidin-4-yl)ethyl)-3-(cyclopropylmethoxy)-5-methoxybenzamide 
• 1428581-57-0 N-(1-(1-(4-(3-cyanophenyl)-1,3,5-triazin-2-yl)piperidin-4-yl)ethyl)-3-(cyclopropylmethoxy)-5-methoxybenzamide 
• 1428582-27-7 N-(1-(1-(2-chloropyrimidin-4-yl)piperidin-4-yl)ethyl)-3-(cyclopropylmethoxy)-5-methoxybenzamide 
• 1621862-74-5 tert-butyl 4-(1-(3-(2-bromophenyl)-4-methoxy-4-oxobut-2-en-2-ylamino)ethyl)piperidine-1-carboxylate 
• 1036027-86-7 tert-butyl 4-[(1R)-1-aminoethyl]piperidine-1-carboxylate 

Relevant articles and documents

MODULATORS OF INDOLEAMINE 2,3-DIOXYGENASE

Provided are IDO inhibitor compounds of Formula I and pharmaceutically acceptable salts thereof, their pharmaceutical compositions, their methods of preparation, and methods for their use in the prevention and/or treatment of diseases. Formula I

ISOXAZOLE CARBOXAMIDE COMPOUNDS

The present disclosure provides substituted isoxazole carboxamide compounds having Formula (I) and the pharmaceutically acceptable salts and solvates thereof, wherein R1, R2, A, X, and Z are defined as set forth in the specification. The present disclosure is also directed to the use of compounds of Formula I to treat a disorder responsive to the blockade of SMYD proteins such as SMYD3 or SMYD2. Compounds of the present disclosure are especially useful for treating cancer.

2′ Biaryl amides as novel and subtype selective M1 agonists. Part I: Identification, synthesis, and initial SAR

Biaryl amides were discovered as novel and subtype selective M1 muscarinic acetylcholine receptor agonists. The identification, synthesis, and initial structure-activity relationships that led to compounds 3j and 4c, possessing good M1 agonist potency and intrinsic activity, and subtype selectivity for M1 over M2-5, are described.