457050-40-7

Basic information

• Product Name: 1-benzyl-1H-benzimidazole-4,7-dione
• CAS NO: 457050-40-7
• Molecular Weight: 238.246
• Mol File: 457050-40-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1-benzyl-1H-benzimidazole-4,7-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 1-benzyl-1H-benzimidazole-4,7-dione(457050-40-7)
• EPA Substance Registry System: 1-benzyl-1H-benzimidazole-4,7-dione(457050-40-7)

Safety Data

• Hazardous Substances Data: 457050-40-7(Hazardous Substances Data)

Upstream product

• 36098-02-9 1-benzyl-4,7-dimethoxy-1H-benzimidazole 
• 150-78-7 1,4-dimethoxybezene 
• 7767-55-7 2,3-Diamino-1,4-dimethoxybenzene dihydrochloride 
• 100-39-0 benzyl bromide 
• 6945-76-2 1,4-dimethoxy-2,3-dinitrobenzene 
• 7711-50-4 4,7-dimethoxybenzimidazole 
• 807317-35-7 1-benzyl-4,7-dihydroxy-1H-benzimidazole 

Downstream Products

• 857053-19-1 1-benzyl-7-methyl-1H-imidazo[4,5-g]quinoline-4,9-dione 
• 857053-18-0 3-benzyl-7-methyl-3H-imidazo[4,5-g]quinoline-4,9-dione 
• 857053-17-9 1-benzyl-8-methyl-1H-imidazo[4,5-g]quinoline-4,9-dione 
• 857053-16-8 3-benzyl-8-methyl-3H-imidazo[4,5-g]quinoline-4,9-dione 

Relevant articles and documents

An improved methodology for the preparation of 4,7-dimethoxy-1H- benzimidazole, a key intermediate in the synthesis of 1-alkyl-1H-benzimidazole- 4,7-diones

We reported an optimized process for the preparation of key intermediate, 4,7-dimethoxy-1H-benzimidazole, from commercially available 1,4-dimethoxybenzene (Overall yield 52%). We successfully applied this methodology to an improved synthesis of 1-benzyl-1

Benzimidazole-4,7-diones as inhibitors of protozoal (Toxoplasma gondii) purine nucleoside phosphorylase

Benzimidazole-4,7-diones derivatives substituted at 1- and/or 2-position have been synthetized and tested as inhibitors of purine nucleoside phosphorylase (PNP), isolated from two strains of Toxoplasma gondii (RH and ME 49). They were identified as inhibi