457061-27-7

Basic information

• Product Name: N-(3-chlorophenyl)-4-(2-fluoropyridin-4-yl)-2-pyrimidinamine
• Synonyms: N-(3-chlorophenyl)-4-(2-fluoropyridin-4-yl)-2-pyrimidinamine
• CAS NO: 457061-27-7
• Molecular Weight: 300.723
• Mol File: 457061-27-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-(3-chlorophenyl)-4-(2-fluoropyridin-4-yl)-2-pyrimidinamine(CAS DataBase Reference)
• NIST Chemistry Reference: N-(3-chlorophenyl)-4-(2-fluoropyridin-4-yl)-2-pyrimidinamine(457061-27-7)
• EPA Substance Registry System: N-(3-chlorophenyl)-4-(2-fluoropyridin-4-yl)-2-pyrimidinamine(457061-27-7)

Safety Data

• Hazardous Substances Data: 457061-27-7(Hazardous Substances Data)

Upstream product

• 22282-70-8 2-fluoro-4-iodopyridine 
• 108-42-9 3-chloro-aniline 
• 361147-25-3 2-chloro-4-(2-fluoropyridin-4-yl)pyrimidine 

Relevant articles and documents

Novel and efficient access to phenylamino-pyrimidine type protein kinase C inhibitors utilizing a Negishi cross-coupling strategy

A novel, short, and efficient synthetic pathway to 3-{4-[2-(3- chlorophenylamino)-pyrimidin-4-yl]-pyridin-2-ylamino}-propanol (CGP 60474) and a series of analogues was developed. The synthetic sequence consisted of a Negishi-type cross-coupling reaction i