45718-99-8 Usage
Cyclic compound
Yes
It has a cyclic structure with a three-membered carbon ring (cyclopropane).
Carbonyl groups
2
The compound contains two carbonyl (C=O) groups, which are key functional groups in organic chemistry.
Chlorine atoms
2
Stereochemistry
(1S-trans)(9CI)
The compound has a specific stereochemistry, with the chlorine atoms in the trans configuration and the carbon atoms in the 1S configuration.
Application
Organic synthesis
It is primarily used in the synthesis of organic compounds, particularly in the production of pharmaceuticals and agrochemicals.
Reagent
Yes
It is often employed as a reagent in the preparation of various organic compounds, especially those with cyclopropane rings.
Reactivity
High
Due to the presence of carbonyl and chlorine atoms, the compound is highly reactive and can participate in various chemical reactions.
Safety precautions
Strict
When handling and using 1,2-Cyclopropanedicarbonyl dichloride in the laboratory, strict safety precautions should be taken to avoid hazardous byproducts and potential health risks.
Hazardous byproducts
Potential
The compound may produce hazardous byproducts during reactions, which is why safety precautions are essential.
Check Digit Verification of cas no
The CAS Registry Mumber 45718-99-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,5,7,1 and 8 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 45718-99:
(7*4)+(6*5)+(5*7)+(4*1)+(3*8)+(2*9)+(1*9)=148
148 % 10 = 8
So 45718-99-8 is a valid CAS Registry Number.
45718-99-8Relevant articles and documents
ALKYLBORONIC ACIDS AS ARGINASE INHIBITORS
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Page/Page column 100, (2020/08/22)
Provided are alkylboronic acids as arginase inhibitors represented by formula (I), or a pharmaceutically acceptable salt, stereoisomer, tautomer, or prodrug thereof and a pharmaceutical composition comprising said compounds.
CYCLOPROPYL-CONTAINING POLYAMINE ANALOGS AS DISEASE THERAPIES
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Page/Page column 38, (2008/12/07)
This disclosure relates to specific polyamine analogs and methods of treating cancer using polyamine analogs. The polyamine analogs have cyclopropyl groups in their internal segments.
On the source of transfer of stereochemical information in ligands for Pd-catalyzed AAA reactions
Trost,Zambrano,Richter
, p. 907 - 909 (2007/10/03)
Examination of a series of ligands for a Pd-catalyzed asymmetric allylic alkylation (AAA) suggests the importance of buttressing effects for creating chiral space for high enantioselectivity.
