457890-62-9

Basic information

• Product Name: (3R,7aS)-5-[2-(2-Methyl-[1,3]dioxolan-2-yl)-ethyl]-3-phenyl-hexahydro-pyrrolo[2,1-b]oxazole-5-carbonitrile
• Synonyms: (3R,7aS)-5-[2-(2-Methyl-[1,3]dioxolan-2-yl)-ethyl]-3-phenyl-hexahydro-pyrrolo[2,1-b]oxazole-5-carbonitrile
• CAS NO: 457890-62-9
• Molecular Weight: 328.411
• Mol File: 457890-62-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (3R,7aS)-5-[2-(2-Methyl-[1,3]dioxolan-2-yl)-ethyl]-3-phenyl-hexahydro-pyrrolo[2,1-b]oxazole-5-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: (3R,7aS)-5-[2-(2-Methyl-[1,3]dioxolan-2-yl)-ethyl]-3-phenyl-hexahydro-pyrrolo[2,1-b]oxazole-5-carbonitrile(457890-62-9)
• EPA Substance Registry System: (3R,7aS)-5-[2-(2-Methyl-[1,3]dioxolan-2-yl)-ethyl]-3-phenyl-hexahydro-pyrrolo[2,1-b]oxazole-5-carbonitrile(457890-62-9)

Safety Data

• Hazardous Substances Data: 457890-62-9(Hazardous Substances Data)

Upstream product

• 37865-96-6 2-(2-bromoethyl)-2-methyl-1,3-dioxolane 
• 195299-15-1 2-cyano-5-oxazolopyrrolidine 

Downstream Products

• 116505-91-0 (R)-2-{(2S,5R)-2-Heptyl-5-[2-(2-methyl-[1,3]dioxolan-2-yl)-ethyl]-pyrrolidin-1-yl}-2-phenyl-ethanol 
• 116561-38-7 (R)-2-{(2R,5R)-2-Heptyl-5-[2-(2-methyl-[1,3]dioxolan-2-yl)-ethyl]-pyrrolidin-1-yl}-2-phenyl-ethanol 
• 116505-90-9 (3R,5R,7aS)-5-[2-(2-Methyl-[1,3]dioxolan-2-yl)-ethyl]-3-phenyl-hexahydro-pyrrolo[2,1-b]oxazole 

Relevant articles and documents

ASYMMETRIC SYNTHESIS XIV: A SHORT AND EFFICIENT SYNTHESIS OF 3,5-DISUBSTITUTED PYRROLIZIDINE ALKALOIDS VIA THE CN(R,S) METHOD

The enantiospecific synthesis of the dextrorotatory enantiomer of the ant venom alkaloid 3-heptyl-5-methylpyrrolidine 11 has been achieved in four steps and 31percent overall yield from the chiral 2-cyano-5-oxazolopyrrolidine synthon 4.On the basis of pre