457959-68-1

Basic information

• Product Name: 1H-Pyrrole-2,5-dione,1-methyl-3-(methylamino)-
• Synonyms: 1H-Pyrrole-2,5-dione,1-methyl-3-(methylamino)-;1H-Pyrrole-2,5-dione, 1-methyl-3-(methylamino)- (9CI);1-methyl-3-(methylamino)-1H-pyrrole-2,5-dione
• CAS NO: 457959-68-1
• Molecular Formula: C₆H₈N₂O₂
• Molecular Weight: 140.13992
• Product Categories: AMINETERTIARY;ALCOHOL
• Mol File: 457959-68-1.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 246.07°C at 760 mmHg
• Flash Point: 102.62°C
• Appearance: /
• Density: 1.261g/cm3
• CAS DataBase Reference: 1H-Pyrrole-2,5-dione,1-methyl-3-(methylamino)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrrole-2,5-dione,1-methyl-3-(methylamino)-(457959-68-1)
• EPA Substance Registry System: 1H-Pyrrole-2,5-dione,1-methyl-3-(methylamino)-(457959-68-1)

Safety Data

• Hazardous Substances Data: 457959-68-1(Hazardous Substances Data)

Usage

Structure

Pyrrole ring with a methyl group and a methylamino group
A five-membered heterocyclic ring structure with one of the members being nitrogen, a methyl group attached to the nitrogen atom, and a methylamino group attached at position 3.
3. Versatile building block in organic synthesis
N-Methylpyrrole-2,5-dione is used as an intermediate compound in the synthesis of various complex organic molecules, making it a valuable component in organic chemistry.
4. Applications in pharmaceuticals and agrochemicals
The compound is used in the production of various pharmaceuticals and agrochemicals due to its unique chemical properties and reactivity.
5. Potential anti-inflammatory and anti-cancer properties
Research has been conducted on N-Methylpyrrole-2,5-dione for its possible therapeutic effects, specifically in the areas of anti-inflammatory and anti-cancer treatments.
6. Use as a reagent in organic chemistry reactions
The compound serves as a reagent in various organic chemistry reactions, facilitating specific chemical transformations and aiding in the synthesis of target molecules.

Upstream product

• 69945-03-5 Methoxymaleinsaeureanhydrid 
• 74-89-5 methylamine 
• 762-42-5 dimethyl acetylenedicarboxylate 
• 874008-12-5 3-Hexin-1,6-dicarbonsaeure-dimethylester 

Downstream Products

• 921447-03-2 C₁₃H₁₄N₂O₄ 
• 607692-31-9 3-(4-methylphenylamino)-1-methyl-1H-pyrrole-2,5-dione 
• 920874-45-9 C₁₂H₁₂N₂O₃ 
• 704873-03-0 1-methyl-3-(phenylamino)-1H-pyrrole-2,5-dione 
• 607692-30-8 3-(benzylamino)-1-methyl-1H-pyrrole-2,5-dione 
• 920941-36-2 1-methyl-3-(m-tolylamino)-1H-pyrrole-2,5-dione 
• 920874-42-6 3-(4-hydroxyphenylamino)-1-methyl-1H-pyrrole-2,5-dione 
• 920941-28-2 3-(4-bromophenylamino)-1-methyl-1H-pyrrole-2,5-dione 
• 920849-76-9 1-methyl-3-(4-nitrophenylamino)pyrrole-2,5-dione 
• 920941-20-4 C₁₁H₉N₃O₄ 
• 921446-99-3 C₁₃H₁₅N₃O₂ 
• 1021119-12-9 1-methyl-3-(p-sulfamidophenylamino)pyrrole-2,5-dione 
• 921447-19-0 2,5,8-trimethyl-dipyrrolo[3,4-e;3',4'-g]isoindole-1,3,4,6,7,9-hexaone 
• 1450999-97-9 1,6-dimethyl-2,2,4-triphenyl-1H-pyrrolo[3,4-b]pyridine-5,7(2H,6H)-dione 

Relevant articles and documents

Cheap and efficient preparation method of benzene triimide and derivative thereof

The invention discloses a preparation method of benzene triimide (BTI) and a derivative thereof, wherein the structural general formula of the compound is represented by a formula I. The preparation method comprises the following steps: under the condition of refluxing in a mixed solution of acetic acid and water, carrying out an intermolecular aromatic ring construction reaction on a maleimide derivative represented by a formula II to obtain the benzene triimide (BTI) and the derivative I thereof. According to the invention, the cheap and easily available raw materials maleic anhydride and maleimide and the cheap and easily available primary amine compound are selected and subjected to simple addition, elimination and amination to rapidly prepare a large amount of maleimide derivatives, and further the maleimide derivatives are subjected to an intermolecular cyclization reaction to rapidly prepare the benzene triimide (BTI) and the derivative thereof in one step, so that the reactionconditions are mild, and the obtained product is stable in air and easy to separate and purify, and has good application prospect.

Lewis acid-promoted cascade reaction of primary amine, 2-butynedioate, and propargylic alcohol: A convenient approach to 1,2-dihydropyridines and 1H-pyrrolo[3,4-b]pyridine-5,7(2H,6H)-diones

1,2-Dihydropyridine-5,6-dicarboxylates were efficiently constructed through a cascade reaction of primary amine, 2-butynedioate and propargylic alcohol in the presence of Lewis acid under mild conditions. As exceptional, 1H-pyrrolo[3,4-b]pyridine-5,7(2H,6