4594-89-2

Basic information

• Product Name: 4-(4-Chlorostyryl)quinoline
• Synonyms: 4-(4-Chlorostyryl)quinoline;4-(p-Chlorostyryl)quinoline
• CAS NO: 4594-89-2
• Molecular Formula: C17H12ClN
• Molecular Weight: 265.7369
• Mol File: 4594-89-2.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 429.9°Cat760mmHg
• Flash Point: 246.4°C
• Appearance: /
• Density: 1.253g/cm³
• Vapor Pressure: 3.39E-07mmHg at 25°C
• Refractive Index: 1.728
• CAS DataBase Reference: 4-(4-Chlorostyryl)quinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-Chlorostyryl)quinoline(4594-89-2)
• EPA Substance Registry System: 4-(4-Chlorostyryl)quinoline(4594-89-2)

Safety Data

• Hazardous Substances Data: 4594-89-2(Hazardous Substances Data)

Usage

InChI:InChI=1/C17H12ClN/c18-15-9-6-13(7-10-15)5-8-14-11-12-19-17-4-2-1-3-16(14)17/h1-12H

Upstream product

• 491-35-0 C₆H₄NCH₂CHCCH₂ 
• 104-88-1 4-chlorobenzaldehyde 
• 19343-78-3 4-methyl-1,2,3,4-tetrahydroquinoline 

Relevant articles and documents

Nickel-Catalyzed Dehydrogenation of N-Heterocycles Using Molecular Oxygen

Herein, an efficient and selective nickel-catalyzed dehydrogenation of five- and six-membered N-heterocycles is presented. The transformation occurs in the presence of alkyl, alkoxy, chloro, free hydroxyl and primary amine, internal and terminal olefin, trifluoromethyl, and ester functional groups. Synthesis of an important ligand and the antimalarial drug quinine is demonstrated. Mechanistic studies revealed that the cyclic imine serves as the key intermediate for this stepwise transformation.