4596-45-6

Basic information

• Product Name: azido(2-tolyl)methanone
• Synonyms: azido(2-tolyl)methanone
• CAS NO: 4596-45-6
• Molecular Weight: 161.163
• Mol File: 4596-45-6.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: azido(2-tolyl)methanone(CAS DataBase Reference)
• NIST Chemistry Reference: azido(2-tolyl)methanone(4596-45-6)
• EPA Substance Registry System: azido(2-tolyl)methanone(4596-45-6)

Safety Data

• Hazardous Substances Data: 4596-45-6(Hazardous Substances Data)

Upstream product

• 933-88-0 ortho-toluoyl chloride 
• 7658-80-2 2-methylbenzohydrazide 
• 118-90-1 ortho-methylbenzoic acid 

Downstream Products

• 120982-35-6 2-methyl-N-(phenylcarbamoyl)benzamide 
• 89-95-2 2-methyl-benzyl alcohol 

Relevant articles and documents

A mild and efficient method for the preparation of acyl azides from carboxylic acids using triphosgene

An efficient use of triphosgene for the preparation of various acyl azides from carboxylic acids and sodium azide is described.

FeCl36H2O-Catalyzed acceleration of the acylation of sodium azide with n-acylbenzotriazoles

Catalyzed by ferric chloride hexahydrate (FeCl36H2O), the acylation of sodium azide with N-acylbenzotriazoles was greatly accelerated in a mixed solvent of acetone and water. Thus, good to excellent yields of a variety of acyl azides were obtained at room temperature in a short time. Furthermore, because of the complete conversion of N-acylbenzotriazoles and the easy removal of the by-product, purification by column chromatography was no longer required, which made the protocol suitable for large-scale preparation.