459841-21-5Relevant articles and documents
Optimization of sulfonamide derivatives as highly selective EP1 receptor antagonists
Naganawa, Atsushi,Matsui, Toshiaki,Ima, Masaki,Yoshida, Koji,Tsuruta, Hiroshi,Yamamoto, Shingo,Yamamoto, Hiroshi,Okada, Hiroki,Maruyama, Takayuki,Nakai, Hisao,Kondo, Kigen,Toda, Masaaki
, p. 7774 - 7789 (2007/10/03)
A series of 4-[(2-{isobutyl[(5-methyl-2-furyl)sulfonyl]amino}phenoxy)methyl]benzoic acids and 4-({2-[isobutyl(1,3-thiazol-2-ylsulfonyl)amino]phenoxy}methyl)benzoic acids were synthesized and evaluated for their EP receptor affinities and EP1 receptor anta
N-PHENYLARYLSULFONAMIDE COMPOUND, DRUG CONTAINING THE COMPOUND AS ACTIVE INGREDIENT, INTERMEDIATE FOR THE COMPOUND, AND PROCESSES FOR PRODUCING THE SAME
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Page 23, (2008/06/13)
(R1 is COOH etc.; R2 is hydrogen, methyl, etc.; R3 and R4 are a combination of methyl and methyl, etc.; R5 is isopropyl etc.; Ar is thiazolyl, pyridyl, 5-methyl-2-furyl each optionally substituted wit