45990-93-0

Basic information

• Product Name: 2-bromo-4,6,N,N-tetramethyl-aniline
• Synonyms: 2-bromo-4,6,N,N-tetramethyl-aniline
• CAS NO: 45990-93-0
• Molecular Weight: 228.132
• Mol File: 45990-93-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-bromo-4,6,N,N-tetramethyl-aniline(CAS DataBase Reference)
• NIST Chemistry Reference: 2-bromo-4,6,N,N-tetramethyl-aniline(45990-93-0)
• EPA Substance Registry System: 2-bromo-4,6,N,N-tetramethyl-aniline(45990-93-0)

Safety Data

• Hazardous Substances Data: 45990-93-0(Hazardous Substances Data)

Upstream product

• 41825-73-4 2-bromo-4,6-dimethylaniline 
• 74-88-4 methyl iodide 
• 95-68-1 2,4-Xylidine 

Downstream Products

• 1401560-20-0 N,N,2,4-tetramethyl-6-(phenylethynyl)aniline 

Relevant articles and documents

Intramolecular Addition of a Dimethylamino C(sp 3)-H Bond across C-C Triple Bonds Using IrCl(DTBM-SEGPHOS)(ethylene) Catalyst: Synthesis of Indoles from 2-Alkynyl- N -methylanilines

Intramolecular addition of a C(sp 3)-H bond of the dimethylamino group across the C-C triple bond in 2-alkynyl- N, N -dimethylanilines is effectively catalyzed by a new iridium complex, IrCl(DTBM-SEGPHOS)(C 2H 4), in mesitylene at 150 °C. The intramolecular C(sp 3)-H addition is followed by double-bond isomerization to afford 3-substituted indoles in good to high yields.