460336-91-8

Basic information

• Product Name: 2-[((S)-2-Acetylamino-3-phenyl-propionyl)-(3-methyl-butyl)-amino]-4-methyl-pentanoic acid (2-benzylcarbamoyl-2-hydroxy-1-methyl-ethyl)-amide
• Synonyms: 2-[((S)-2-Acetylamino-3-phenyl-propionyl)-(3-methyl-butyl)-amino]-4-methyl-pentanoic acid (2-benzylcarbamoyl-2-hydroxy-1-methyl-ethyl)-amide
• CAS NO: 460336-91-8
• Molecular Weight: 580.768
• Mol File: 460336-91-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-[((S)-2-Acetylamino-3-phenyl-propionyl)-(3-methyl-butyl)-amino]-4-methyl-pentanoic acid (2-benzylcarbamoyl-2-hydroxy-1-methyl-ethyl)-amide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[((S)-2-Acetylamino-3-phenyl-propionyl)-(3-methyl-butyl)-amino]-4-methyl-pentanoic acid (2-benzylcarbamoyl-2-hydroxy-1-methyl-ethyl)-amide(460336-91-8)
• EPA Substance Registry System: 2-[((S)-2-Acetylamino-3-phenyl-propionyl)-(3-methyl-butyl)-amino]-4-methyl-pentanoic acid (2-benzylcarbamoyl-2-hydroxy-1-methyl-ethyl)-amide(460336-91-8)

Safety Data

• Hazardous Substances Data: 460336-91-8(Hazardous Substances Data)

Upstream product

• 460049-36-9 N-benzyl-2-formyloxy-3-formamidobutyric amide 
• 395644-82-3 N-benzyl-2-hydroxy-3-nitrobutyric amide 
• 395644-85-6 N-benzyl-2-hydroxy-3-aminobutyric amide 
• 100-46-9 benzylamine 
• 88393-56-0 (2R,3R)-N¹,N⁴-dibenzyl-2,3-dihydroxysuccinamide 
• 32331-52-5 N-benzyl glyoxylic amide 
• 107-85-7 1-amino-3-methylbutane 
• 2018-61-3 (S)-2-acetylamino-3-phenylpropanoic acid 
• 590-86-3 isovaleraldehyde 
• 460048-60-6 formic acid 1-benzylcarbamoyl-2-isocyano-propyl ester 

Relevant articles and documents

Synthesis of a peptidomimetic HCMV protease inhibitor library

The human cytomegalovirus (HCMV) protease catalyzes the maturational process of the herpes virus assembly protein and plays a key role during the manufacture of viral capsid, and so is an attractive target for potential anti-herpes-virus agents with novel structures and new mechanisms. In this work, a peptidomimetic skeleton was designed and a chemical library containing 32 compounds with different substitutions on the skeleton was prepared by the oxidation of a precursor library, which was constructed from four types of building blocks: 4 carboxylic acids, 2 amines, 2 aldehydes and 2 isocyanides, based on multicomponent condensation following liquid phase strategies. The syntheses of the key building block isocyanides are presented.