461451-35-4 Usage
Description
2-IMIDAZO[1,2-A]PYRIMIDIN-7-YL-PROPAN-2-OL is a synthetic chemical compound characterized by an imidazopyrimidinyl ring fused to a propanol group. This unique structure may confer potential pharmacological properties, making it a candidate for further research and development in various applications.
Uses
Used in Pharmaceutical Industry:
2-IMIDAZO[1,2-A]PYRIMIDIN-7-YL-PROPAN-2-OL is used as a potential pharmaceutical agent for its possible pharmacological properties. The specific reasons for its use and the exact applications would require further investigation and validation through research and experimentation.
Used in Chemical Research:
In the field of chemical research, 2-IMIDAZO[1,2-A]PYRIMIDIN-7-YL-PROPAN-2-OL serves as a subject for studying the effects of its unique imidazopyrimidinyl and propanol group fusion on chemical behavior and interactions with other compounds. This research could lead to the discovery of new applications and uses for the compound.
Check Digit Verification of cas no
The CAS Registry Mumber 461451-35-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,6,1,4,5 and 1 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 461451-35:
(8*4)+(7*6)+(6*1)+(5*4)+(4*5)+(3*1)+(2*3)+(1*5)=134
134 % 10 = 4
So 461451-35-4 is a valid CAS Registry Number.
461451-35-4Relevant articles and documents
Imidazo[1,2-a]pyrimidines as functionally selective and orally bioavailable GABAAα2/α3 binding site agonists for the treatment of anxiety disorders
Goodacre, Simon C.,Street, Leslie J.,Hallett, David J.,Crawforth, James M.,Kelly, Sarah,Owens, Andrew P.,Blackaby, Wesley P.,Lewis, Richard T.,Stanley, Joanna,Smith, Alison J.,Ferris, Pushpinder,Sohal, Bindi,Cook, Susan M.,Pike, Andrew,Brown, Nicola,Wafford, Keith A.,Marshall, George,Castro, José L.,Atack, John R.
, p. 35 - 38 (2007/10/03)
A series of high-affinity GABAA agonists with good oral bioavailability in rat and dog and functional selectivity for the GABA Aα2 and -α3 subtypes is reported. The 7-trifluoromethylimidazopyrimidine 14g and the 7-propan-2-olimidazopyrimidine 14k are anxiolytic in both conditioned and unconditioned animal models of anxiety with minimal sedation observed at full BZ binding site occupancy.
