4620-51-3

Basic information

• Product Name: 1-(2-ethylphenyl)-3-[(4-methylpyrimidin-2-yl)sulfanyl]pyrrolidine-2,5-dione
• Synonyms: 1-(2-Ethyl-phenyl)-3-(4-methyl-pyrimidin-2-ylsulfanyl)-pyrrolidine-2,5-dione; 1-(2-Ethylphenyl)-3-[(4-methylpyrimidin-2-yl)sulfanyl]pyrrolidine-2,5-dione; 2,5-Pyrrolidinedione, 1-(2-ethylphenyl)-3-[(4-methyl-2-pyrimidinyl)thio]-
• CAS NO: 4620-51-3
• Molecular Formula: C₁₂H₁₁NO₂
• Molecular Weight: 327.4008
• Mol File: 4620-51-3.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 589°C at 760 mmHg
• Flash Point: 310°C
• Density: 1.33g/cm³
• Vapor Pressure: 7.47E-14mmHg at 25°C
• Refractive Index: 1.648
• CAS DataBase Reference: 1-(2-ethylphenyl)-3-[(4-methylpyrimidin-2-yl)sulfanyl]pyrrolidine-2,5-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-ethylphenyl)-3-[(4-methylpyrimidin-2-yl)sulfanyl]pyrrolidine-2,5-dione(4620-51-3)
• EPA Substance Registry System: 1-(2-ethylphenyl)-3-[(4-methylpyrimidin-2-yl)sulfanyl]pyrrolidine-2,5-dione(4620-51-3)

Safety Data

• Hazardous Substances Data: 4620-51-3(Hazardous Substances Data)

Usage

Description

1-(2-ethylphenyl)-3-[(4-methylpyrimidin-2-yl)sulfanyl]pyrrolidine-2,5-dione is a complex chemical compound characterized by a pyrrolidine-2,5-dione backbone and the presence of sulfanyl and pyrimidin-2-yl substituents. This structure suggests that the compound may possess unique pharmacological properties and the potential to interact with various biological targets, making it a promising candidate for further investigation in the field of medicinal chemistry.

Uses

Used in Pharmaceutical Industry:
1-(2-ethylphenyl)-3-[(4-methylpyrimidin-2-yl)sulfanyl]pyrrolidine-2,5-dione is used as a potential drug candidate for its possible pharmacological activities. 1-(2-ethylphenyl)-3-[(4-methylpyrimidin-2-yl)sulfanyl]pyrrolidine-2,5-dione's structure and properties make it an interesting target for research and development, with the aim of identifying its therapeutic potential and possible applications in treating various medical conditions.
Additionally, if the compound has demonstrated specific applications in other industries, they can be listed as follows:
Used in [Application Industry]:
1-(2-ethylphenyl)-3-[(4-methylpyrimidin-2-yl)sulfanyl]pyrrolidine-2,5-dione is used as [application type] for [application reason].

Upstream product

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• 23112-27-8 N-((Z)-1-methyl-3-oxobut-1-enyl)benzamide 
• 29397-21-5 Diacetyldiazomethan 

Downstream Products

• 58436-18-3 1-(4-bromomethyl-2-phenyl-oxazol-5-yl)-ethanone 
• 58436-20-7 (5-acetyl-2-phenyl-oxazol-4-yl)-acetic acid methyl ester 
• 66882-19-7 (5-acetyl-2-phenyl-oxazol-4-yl)-acetic acid ethyl ester 
• 58436-23-0 4t-methyl-2-phenyl-(3ar,7ac)-3a,4,7,7a-tetrahydro-pyrano[4,3-d]oxazol-6-one 
• 58436-24-1 4t-methyl-2-phenyl-(4ar,7at)-4,4a,7,7a-tetrahydro-furo[3,2-d][1,3]oxazin-6-one 
• 58436-26-3 4-methyl-2-phenyl-4,7-dihydro-pyrano[4,3-d]oxazol-6-one 
• 58436-25-2 O¹-acetyl-3-amino-N,O⁴-(Ξ)-benzylidene-ξ-DL-lyxo-2,3,6-trideoxy-hexopyranose 
• 58436-17-2 4-methyl-2-phenyl-pyrano[4,3-d]oxazol-6-one 
• 58436-19-4 (5-acetyl-2-phenyl-oxazol-4-yl)-acetonitrile 
• 58436-21-8 (5-acetyl-2-phenyl-oxazol-4-yl)-acetic acid 

Relevant articles and documents

Rhodium(I)-Catalyzed Coupling-Cyclization of C=O Bonds with α-Diazoketones

An unprecedented intermolecular nucleophilic attack of C=X bonds (X = O and S) on the rhodium(I)-carbenes has been developed. This transformation allows for the coupling-cyclization of aroylamides with α-diazoketones and provides concise access to 2,4,5-trisubstituted 1,3-oxazoles and 1,3-thiazoles with a broad tolerance of functional groups.

Copper-catalyzed oxidative cyclization of arylamides and ?2-diketones: New synthesis of 2,4,5-trisubstituted oxazoles

A novel copper catalyzed approach to oxazoles via enamide intermediates was developed from benzamides and ?2-diketones. The successive condensation and cyclization reactions afforded various 2,4,5-trisubstituted oxazoles in good yields.

Synthesis of substituted oxazoles from enamides

Annulation of enamides into 2,5- and 2,4,5-substituted oxazoles by NBS/Me2S in the presence of mild base has been achieved. The reaction conditions are simple and tolerant to a wide variety of substituents including both electron-donating and withdrawing groups to produce oxazoles in one-pot without further purification of the intermediate.