46230-78-8

Basic information

• Product Name: 2-morpholinoethyl methanesulfonate
• CAS NO: 46230-78-8
• Molecular Formula: C₇H₁₅NO₄S
• Molecular Weight: 209.2633
• Mol File: 46230-78-8.mol
• Article Data: 19

Chemical Properties

• Boiling Point: 363.116°C at 760 mmHg
• Flash Point: 173.407°C
• Density: 1.231g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.483
• CAS DataBase Reference: 2-morpholinoethyl methanesulfonate(CAS DataBase Reference)
• NIST Chemistry Reference: 2-morpholinoethyl methanesulfonate(46230-78-8)
• EPA Substance Registry System: 2-morpholinoethyl methanesulfonate(46230-78-8)

Safety Data

• Hazardous Substances Data: 46230-78-8(Hazardous Substances Data)

Upstream product

• 622-40-2 2-(morpholin-4-yl)ethanol 
• 124-63-0 methanesulfonyl chloride 

Downstream Products

• 73735-24-7 (3-Benzyl-3H-imidazo[4,5-b]pyridin-2-yl)-[1-(2-morpholin-4-yl-ethyl)-piperidin-4-yl]-amine 
• 1018895-21-0 4-(2-(5-fluoro-2-nitrophenoxy)ethyl)morpholine 
• 895156-54-4 [6-(benzyloxy)-1-(2-morpholin-4-ylethyl)-1H-indol-3-yl](2,2,3,3-tetramethylcyclopropyl)methanone 
• 895157-53-6 [5-benzyloxy-1-(2-morpholin-4-yl-ethyl)-1H-indol-3-yl]-(2,2,3,3-tetramethyl-cyclopropyl)-methanone 
• 72395-48-3 1-<2-(4-morpholinyl)ethyl>-1H-indole 
• 1273387-11-3 [2-(morpholin-4-yl)ethyl] (6-{(pyridin-2-ylsulfonyl)[4-(thiazol-2-yl)benzyl]aminomethyl}pyridin-2-ylamino)acetate 
• 660395-39-1 4-(2-azido-ethyl)-morpholine 
• 1316652-29-5 C₁₅H₁₉N₅O₃ 
• 1431773-42-0 N-(6-(2-methylpyrrolidin-1-yl)pyridin-2-yl)-6-(4-(2-morpholinoethoxy)phenyl)imidazo[1,2-b]pyridazin-8-amine 
• 1431773-40-8 N-(6-(2-methylpyrrolidin-1-yl)pyridin-2-yl)-6-(3-(2-morpholinoethoxy)phenyl)imidazo[1,2-b]pyridazin-8-amine 

Relevant articles and documents

PROTEIN TYROSINE PHOSPHATASE INHIBITORS AND METHODS OF USE THEREOF

Provided herein are compounds, compositions, and methods useful for inhibiting protein tyrosine phosphatase, e.g, protein tyrosine phosphatase non-receptor type 2 (PTPN2) and/or protein tyrosine phosphatase non-receptor type 1 (PTPN1), and for treating related diseases, disorders and conditions favorably responsive to PTPN1 or PTPN2 inhibitor treatment, e.g, a cancer or a metabolic disease.

Novel kinase inhibitor

The present invention provides a novel pan-RAF kinase inhibitor. The novel pan-RAF kinase inhibitor comprises a compound shown in a formula (I) or a pharmaceutically acceptable salt, solvate, ester, acid, metabolite, or prodrug of the compound. The invention also provides the use and method of the compound shown in the formula (I) for the prevention or treatment of disorders associated with RAF and/or RAS kinase activity.

PROTEIN TYROSINE PHOSPHATASE INHIBITORS AND METHODS OF USE THEREOF

Provided herein are compounds, compositions, and methods useful for inhibiting protein tyrosine phosphatase, e.g., protein tyrosine phosphatase non-receptor type 2 (PTPN2) and/or protein tyrosine phosphatase non-receptor type 1 (PTPN1), and for treating related diseases, disorders and conditions favorably responsive to PTPN1 or PTPN2 inhibitor treatment, e.g., a cancer or a metabolic disease.