462655-05-6Relevant articles and documents
Catalytic enantioselective synthesis of β2-amino acids
Davies, Huw M. L.,Venkataramani, Chandrasekar
, p. 2197 - 2199 (2007/10/03)
A very direct approach for the synthesis of β-amino esters is provided by catalytic asymmetric C-H activation by means of carbenoid-induced C-H insertion (see scheme; Boc = butyloxycarbonyl; TFA = trifluoroacetic acid). The reactions described herein represent the first regioselective intermolecular C-H insertions occurring at a methyl site.
